Results 81 to 90 of about 100,521 (261)

Periportal and Puncture Capsulotomy Techniques Have Similar Outcomes to Traditional Capsulotomies With Closure in Hip Arthroscopy: A Systematic Review and Meta‐analysis of 2‐Year Outcomes

Arthroscopy, EarlyView.
Purpose To systematically evaluate capsulotomy techniques through patient‐reported outcome measures, rates of revision arthroscopy, conversion to total hip arthroplasty, and achievement of clinically meaningful outcomes. Methods PubMed, Scopus, and Embase databases were queried in June 2024 for studies that could be used to compare capsular management ...
Brandon J. Allen, Jeffrey S. Mun, Srish S. Chenna, Rachel L. Poutre, Kieran S. Dowley, Stephen M. Gillinov, Bilal S. Siddiq, Nathan J. Cherian, Chris T. Eberlin, Scott D. Martin   +9 more
wiley   +1 more source

PRL-3 activates mTORC1 in Cancer Progression

, 2015
PRL-3, a metastasis-associated phosphatase, is known to exert its oncogenic functions through activation of PI3K/Akt, which is a key regulator of the rapamycin-sensitive mTOR complex 1 (mTORC1), but a coherent link between PRL-3 and activation of mTOR ...
Shen, H.-M, Gupta, Abhishek, Zeng, Qi, Gupta, A, Ye, Z, Park, J.E, Shen, Han-Ming, Al-Aidaroos, Abdul Qader Omer, Park, Jung Eun, Lin, Youbin, Zhang, S.D, Al-Aidaroos, A.Q.O, Ye, Zu, Zhang, Shu Dong, Yuen, H.F, Yuen, Hiu Fung, Lin, Y, Zeng, Q   +17 more
core   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Beyond knowledge: Cultivating noncognitive skills and attributes through anatomy education

Anatomical Sciences Education, EarlyView.
Abstract Anatomy education has historically prioritized cognitive knowledge acquisition and technical skills, such as spatial awareness and manual dexterity. Noncognitive attributes, essential for early‐stage learners, such as social skills, motivation, emotional intelligence, self‐regulation, self‐efficacy, and resilience, have remained comparatively ...
Renato Lopes Previdelli, Sarah Beth Channon   +1 more
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Purification of PRL receptors from toad kidney: comparisons with rabbit mammary PRL receptors

, 1988
The binding characteristics of the prolactin (PRL) receptors present in toad (Bufo marinus) kidneys were investigated and compared to those of PRL receptors present in rabbit mammary glands.
J. P. Kraehenbuhl, M. L. Aubert, M. Dunand, B. C. Rossier   +3 more
core   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

“It's the Exact Same Treatment … Except Only 5 Min Away”: A RE‐AIM Evaluation of a Speech‐Language Pathology Shared‐Care Model for Rural Patients With Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Challenges accessing post‐treatment speech‐language pathology (SLP) services can add to treatment burden for rural patients with head and neck cancer (HNC). Hence, the aim of this study was to evaluate a shared‐care SLP service designed to support local SLP access for patients with HNC, using the RE‐AIM framework.
Corey Patterson, Elizabeth C. Ward, Rebecca L. Packer, Jasmine Foley, Laurelie R. Wishart, Clare L. Burns, Sally Pether, Wendy Comben   +7 more
wiley   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source