Results 121 to 130 of about 111,764 (305)

Increased expression of PRL-1 protein correlates with shortened patient survival in human hepatocellular carcinoma

, 2012
[[abstract]]"Background The purposes of the current study were to investigate whether overexpression of the PRL-1 is clinically relevant to hepatocellular carcinoma (HCC) and whether expression patterns of PRL-1 in HCC have diagnostic and prognostic ...
蔡進發;Jeffrey, J.P.Tsai;胡若梅;Hu, Rouh-Mei
core  

The precursor deficit in PRL-deficient mice cannot be rescued by the addition of PRL or KCl-induced depolarizarion.

, 2013
(A) The addition of 2 ng/ml PRL to cultures of hippocampal cells from adult PRL+/+ mice resulted in a significant increase in neurosphere numbers ...
Tara L. Walker (308979), Eirinn W. Mackay (308981), Daniel G. Blackmore (297180), Margaretha M. Koudijs (308980), Adam S. Hamlin (289993), Rupert W. Overall (122762), Perry F. Bartlett (205720), Jana Vukovic (297181), Alex M. Sykes (308982)   +8 more
core   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

How Organizations Learn and Innovate to Institutionalize Generative AI: Trust, Feedback Loops, and Cultural Friction

AI &Innovation, EarlyView.
ABSTRACT This study examines how organizations advance in their use of Generative AI (GenAI) tools after initial adoption with particular attention to the dynamics of trust, cultural resistance, and feedback mechanisms. Grounded in organizational learning theory and institutional theory, we propose a framework that captures the factors influencing how ...
Surajit Bag, Gautam Srivastava, Santosh Kumar Shrivastav, Daniel Rees   +3 more
wiley   +1 more source

Niewypowiedziany przełom. Wpływ wydarzeń roku 1980 na działalność i sprawozdawczość Delegatury Głównego Urzędu Kontroli Prasy, Publikacji i Widowisk w Białymstoku

Studia Podlaskie
W artykule zostały omówione istotne aspekty pracy białostockich cenzorów w dobie kryzysu, w szczególnej, przełomowej politycznie dekadzie lat 70. i 80. w PRL.
Helena Chwiedosik
doaj   +1 more source

Hiperprolaktynemia - pułapki w oznaczaniu PRL [PDF]

, 2006
Prolactin (PRL) is one of the most commonly assessed hormones, and hyperprolactinaemia seems to be often endocrine disorder. Hyperprolactinaemia is not a disease, but only a symptom indicating relevant medical conditions to be diagnosed and properly ...
Zgliczyński, Wojciech; Klinika Endokrynologii Centrum Medycznego Kształcenia Podyplomowego, Zdunowski, Piotr   +1 more
core  

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Architekci w Cepelii. Między państwowym biurem projektowym a wolnym zawodem. Przykład Spółdzielni Pracy Twórczej Architektów i Artystów Plastyków „Espea”

Quart
The paper examines the origins and activities of the Espea design cooperative, one of the first architectural cooperatives operating within the structures of Cepelia since the 1980s. The author interprets Espea as a response to the crisis of state design
Anna Wiszniewska
doaj   +1 more source

Crime fiction in the period of PRL (PRL crime fiction) [PDF]

, 2014
A novel with a socialist police motif is a subgenre of PRL crime fiction which appeared in the Communist Blok countries. Its characteristic features are as follows: the over-persuasive function, glorification of the socialist police (MO), inspirations ...
Skotarczak, Dorota
core  

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

The Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy, Alice Nishigaki, Matthew C. Gage, Renato L. Previdelli   +3 more
wiley   +1 more source