Results 61 to 70 of about 218,901 (254)

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Stereoelectronic Effects in the 02-mediated Autoxidation of Reduced Folate Derivatives

Pteridines, 1993
For over forty years pteridinologists have studied the O2-mediated autoxidation of reduced folate derivatives. This effort has resulted in the identification of several transient intermediates and many products. Until now.
Fitzhugh Anthony L.
doaj   +1 more source

EKOLOGIA I OCHRONA ŚRODOWISKA W POLSKIEJ RZECZPOSPOLITEJ LUDOWEJ

Humanities and Social Sciences, 2018
Ideologia komunistyczna zakładała bezwzględne podporządkowanie przyrody człowiekowi mogącemu dowolnie zmieniać i kształtować oblicze Ziemi. Rozpoczęto realizowanie wielkich programów przekształcania środowiska przyrodniczego, które już w krótkim czasie ...
Radosław Domke
doaj   +1 more source

Criticality in inhomogeneous magnetic systems: Application to quantum ferromagnets

, 2007
We consider a $\phi^4$-theory with a position-dependent distance from the critical point. One realization of this model is a classical ferromagnet subject to non-uniform mechanical stress.
A. I. Larkin, A. I. Larkin, D. Belitz, L. D. Landau, Ronojoy Saha, S.-K. Ma, S. A. Pikin, S. A. Pikin, T. R. Kirkpatrick   +8 more
core   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

Advanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao, Shan Xu, You Zou, Rui Yang, Han Zheng, Jia‐Yu Liu, Hui‐Ming Fan, Yuan‐Yuan Zhang, Yong‐Gang Kong, Wo‐Er Jiao, Shi‐Ming Chen   +10 more
wiley   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Rola Józefa Tejchmy w kryzysie grudniowym 1970 r. Meandry rozgrywek na szczytach kierownictwa PZPR

Acta Universitatis Lodziensis: Folia Historica
Celem artykułu jest przybliżenie roli Józefa Tejchmy podczas kryzysu grudniowego 1970 r. Praca analizuje działania Tejchmy, próbując określić wagę roli odegranej przez niego oraz jego postawę w dniach kryzysu.
Jakub Kuliś
doaj   +1 more source

Halina Evert-Kappesowa, (Co-)Founder of Post-War Polish Byzantine Studies

Studia Ceranea, 2020
This article aims to expand information on the life and academic career of a historian from Łódź, the co-founder of Polish post-war Byzantine studies – Halina Evert-Kappesowa.
Jolanta Kolbuszewska
doaj   +1 more source

Schulman Replies

, 2000
This is a reply to a comment of Casati, Chirikov and Zhirov (PRL 85, 896 (2000)) on PRL 83, 5419 (1999).
G. Casati, J. L. Lebowitz, L. S. Schulman, L. S. Schulman, L. S. Schulman, L. S. Schulman, N. Wiener, R. Penrose, T. Gold   +8 more
core   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source