Results 71 to 80 of about 251,912 (281)

Possible Stimulatory Effect of Quercetin on Secretion of Selected Pituitary Hormones

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Quercetin is found in various types of foods such as apples, red onions, grapes, berries, citrus fruits, cherries, broccoli, tea etc. It is characterized by antioxidative, anti-carcinogenic, bacteriostatic and anti-inflammatory effects on the animal ...
Eva Tušimová   +4 more
doaj  

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Reply to Comment on "Roughness of Interfacial Crack Fronts: Stress-Weighted Percolation in the Damage Zone"

open access: yes, 2004
This is the reply to a Comment by Alava and Zapperi (cond-mat/0401568) on Schmittbuhl, Hansen and Batrouni, PRL, 90, 045505 (2003)
Batrouni, G. George   +2 more
core   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

open access: yesAdvanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang   +9 more
wiley   +1 more source

Hot electron relaxation: A review of the two temperature model for ultrafast non-equilibrium phenomena in metals

open access: yesAPL Quantum
The famous Two-Temperature Model (TTM) used extensively in the investigations of energy relaxation in photo excited systems originated in the seminal work of Kaganov et al. [Sov. J. Exp. Theor. Phys. 4, 173 (1957)]. The idea that with an ultrashort laser
Navinder Singh
doaj   +1 more source

Komiksy superbohaterskie wydawnictw Marvel i DC w dyskursie naukowym i krytycznym okresu PRL

open access: yesLiteratura i Kultura Popularna
In the United States, superhero comic books achieved widespread popularity in the 1930s, and during the next decades of the 20th century they grew to become one of the most important elements of American culture. Nowadays, characters like Captain America,
Szymon Makuch
doaj   +1 more source

EKOLOGIA I OCHRONA ŚRODOWISKA W POLSKIEJ RZECZPOSPOLITEJ LUDOWEJ

open access: yesHumanities and Social Sciences, 2018
Ideologia komunistyczna zakładała bezwzględne podporządkowanie przyrody człowiekowi mogącemu dowolnie zmieniać i kształtować oblicze Ziemi. Rozpoczęto realizowanie wielkich programów przekształcania środowiska przyrodniczego, które już w krótkim czasie ...
Radosław Domke
doaj   +1 more source

Quantum Smoluchowski equation: A systematic study

open access: yes, 2010
The strong friction regime at low temperatures is analyzed systematically starting from the formally exact path integral expression for the reduced dynamics.
A. G. Redfield   +9 more
core   +1 more source

Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia

open access: yesEMBO Molecular Medicine, 2013
FLT3‐ITD mutations are prevalent mutations in acute myeloid leukaemia (AML). PRL‐3, a metastasis‐associated phosphatase, is a downstream target of FLT3‐ITD.
J. Park   +10 more
semanticscholar   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang   +12 more
wiley   +1 more source

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