Results 61 to 70 of about 21,236 (231)
There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present ethical concerns. The development of relevant in vitro assays is part of the solution.
Jason Szeto +17 more
doaj +1 more source
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples +10 more
wiley +1 more source
Abstract Objective Appropriate endpoints for daily antiseizure medications may differ from those for intermittent, immediate‐use seizure medications (ISMs). The observed interval between seizure clusters over time (SEIzure interVAL [SEIVAL]) has been proposed as a novel effectiveness endpoint for ISMs.
Wesley T. Kerr +4 more
wiley +1 more source
Degree design - exploring creativity from the start [PDF]
Curriculum design has occupied the attention of academics throughout the ages. In design related degrees the subject matter itself should inspire careful consideration of the structure of an academic programme.
Childs, PRN
core
Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger +10 more
wiley +1 more source
PRN sedative prescribing in the elderly [PDF]
Doctors admitting elderly patients to hospital frequently prescribe sedation as required or pro re nata (prn). They may do this for a variety of reasons, including inexperience, habit and to avoid disturbing a medical colleague at night.
Rebecca Rawesh +2 more
openaire +1 more source
Molecular mechanisms of loss of Prn expression.
(A) Deletion of the Prn signal sequence (prn1ΔSS). Prn− isolates (n = 24) have an 84-bp deletion, resulting in a 28-amino acid deletion (Val9 to Trp36) in the N-terminal region. (B) IS481 insertion mutation in Prn1 gene (prn1::IS481). Eight Prn− isolates
Nao Otsuka (183789) +6 more
core +1 more source
Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres +4 more
wiley +1 more source
Children's postoperative 'pro re nata' (PRN) analgesia: Nurses' administration practices
'Aims and objectives': This paper reports a study aimed at exploring the nursing practices associated with the administration of pro re nata (PRN) postoperative analgesia to children, and at gaining a preliminary understanding of the decisions that ...
Usher, Kim +2 more
core +2 more sources
Purpose. To compare the functional and anatomical outcomes of one dose and three loading doses followed by the pro re nata (PRN) regimen in Chinese neovascular age-related macular degeneration (nvAMD) (including polypoidal choroidal vasculopathy (PCV ...
Fenghua Wang +14 more
doaj +1 more source

