Results 81 to 90 of about 170,345 (285)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Language sample analysis for Spanish speakers [PDF]

open access: yes, 2015
textThe purpose of this project was to develop a Spanish language sample analysis (LSA) scoring procedure for English-Spanish bilinguals used to guide clinicians in developing language goals and monitoring progress on those goals. A Spanish LSA procedure
Pool, Molly Lauren
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Arabic parsing using grammar transforms [PDF]

open access: yes, 2010
We investigate Arabic Context Free Grammar parsing with dependency annotation comparing lexicalised and unlexicalised parsers. We study how morphosyntactic as well as function tag information percolation in the form of grammar transforms (Johnson, 1998 ...
Tounsi, Lamia, van Genabith, Josef
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

The pro-drop parameter and second language acquisition

open access: yesTrabalhos em Linguística Aplicada, 2012
Sem ...
Sonia Maria L. Cyrino
doaj  

The Interpretation of Null Subjects in a Radical Pro-drop Language: Topic Chains and Discourse-semantic Requirements in Chinese

open access: yesStudies in Chinese Linguistics, 2019
Based on original data collected through an online experiment, evidence is provided in this paper that the interpretation of null subjects in a radical pro-drop language like Chinese relies on the topic criterion proposed for consistent and partial pro ...
Frascarelli Mara, Casentini Marco
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Sobre a aquisição de uma língua semi-pro-drop como L2 = On the L2 acquisition of a semi-pro-drop language

open access: yesLetras de Hoje, 2011
Este estudo apresenta um experimento sobre a aquisição de L2 da Restrição do Pronome Pleno (RPP, Overt Pronoun Constraint), um princípio universal que refere ao fato que as línguas de sujeito nulo não permitem que um pronome pleno seja ligado por um ...
Molsing, Karina Veronica
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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