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Role of PPARG (Pro12Ala) in Malaysian type 2 diabetes mellitus patients
International Journal of Diabetes in Developing Countries, 2016Diabetes is one of the major lifestyle disorders in the world. Asian countries, including Malaysia, contribute with more than 60 % of the world’s diabetic population. The single nucleotide polymorphisms (SNPs) of the peroxisome proliferator-activated receptor gamma (PPARG) have been identified as one of the key regulators of glucose and lipid ...
Darishiani Paramasivam +5 more
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POLIMORFISMO PRO12ALA DEL GEN PPARG2 EN PACIENTES CON OBESIDAD MORBIDA
ACTA CIENTIFICA DE LA SOCIEDAD VENEZOLANA DE BIOANALISTAS ESPECIALISTASExisten numerosos genes que regulan diferentes funciones en el organismo y cuya expresión se ve afectada por factores ambientales, determinando el fenotipo del individuo. Entre estos se encuentran el gen PPARG2, que es un factor de transcripción implicado en el mantenimiento de la homeostasis de los lípidos, regulando las vías anabólicas.
Angela Gomes Garcia +4 more
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[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004Gene PPARgamma is one of the pivotal factors that influence adipocyte differentiation. It is transcriptional factor that plays a crucial role in the regulation of genes involved in lipid utilisation and storage as well as insulin action. The aim of this study was to evaluate whether PPARgamma Pro12Ala and Pro115Gln polymorphisms are connected with ...
Bozena, Bidzińska +5 more
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2007
Introduction: Metabolic syndrome (MetS) is defined as a cluster of risk factors for cardiovascular disease. Aim of this study was to evaluate the association between metabolic syndrome components (ATPIII) and the presence of two common polymorphisms (Pro12Ala and ACE I/D) in a cohort of obese individuals. Materials and methods: 140 subjects (M/F= 44/96)
DALLA NORA, Edoardo +7 more
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Introduction: Metabolic syndrome (MetS) is defined as a cluster of risk factors for cardiovascular disease. Aim of this study was to evaluate the association between metabolic syndrome components (ATPIII) and the presence of two common polymorphisms (Pro12Ala and ACE I/D) in a cohort of obese individuals. Materials and methods: 140 subjects (M/F= 44/96)
DALLA NORA, Edoardo +7 more
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SP436 – The Pro12Ala polymorphism of PPARG gene and OSAHS
Otolaryngology - Head and Neck Surgery, 2009Shan-Kai Yin, Hai-Bo Shi, Jian Guan
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Diet and PPARG2 Pro12Ala Polymorphism Interactions in Relation to Cancer Risk: A Systematic Review
Nutrients, 2021Kate T Tran, Gerd Bobe, Zhenzhen Zhang
exaly
Решение конкретных задач, имеющие огромное значение как для спорта в целом, так и для каждого человека лично, связано с пониманием влияния механизма наследственности на здоровье и повышение спортивных результатов человека. Целью нашей работы явилось исследование частоты встречаемости генотипов полиморфизма Pro12Ala гена PPARG у узбекских спортсменов ...
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The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
Nature Genetics, 2000David M Altshuler +2 more
exaly