Results 211 to 220 of about 3,465 (237)

Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis

Neuroscience Letters, 2009
PPARs belong to a receptor family of ligand-activated transcription factors involved in the regulation of inflammation. A crucial role both for PPARgamma and for PPARalpha for the regulation of autoimmunity has been clearly demonstrated, as receptor agonists had beneficial effects on several CD4(+) T cell mediated autoimmune diseases including ...
Luisa, Klotz, Stephan, Schmidt, Reinhard, Heun, Thomas, Klockgether, Heike, Kölsch   +4 more
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Association of PPARG Gene Polymorphisms Pro12Ala with Type 2 Diabetes Mellitus: A Meta-analysis

Current Diabetes Reviews, 2019
Background:Previous studies suggested that the single nucleotide polymorphisms of Pro12Ala located within the PPARG gene were significantly associated with the T2DM. Recently, the genetic studies on Pro12Ala were conducted in the different ethnic groups and the results of each study were shown to be inconsistent. Moreover, the systematic review has not
Junyan, Li, Xiaohong, Niu, JianBo, Li, Qingzhong, Wang   +3 more
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COMT Val158Met and PPARγ Pro12Ala polymorphisms and susceptibility to Alzheimer’s disease: a meta-analysis

Neurological Sciences, 2014
The aim of this study was to explore whether the catechol-O-methyltransferase (COMT) Val158Met or the peroxisome proliferator-activated receptor-gamma (PPARγ) Pro12Ala polymorphisms are associated with susceptibility to Alzheimer's disease (AD).
Young Ho, Lee, Gwan Gyu, Song
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The association of Pro12Ala polymorphism in PPARγ2 with lower carotid artery IMT in Japanese

Diabetes Research and Clinical Practice, 2003
In this study, the association of the Pro12Ala peroxisome proliferator-activated receptor gamma2 (PPARgamma2) polymorphism with atherosclerosis was examined in a Japanese Type 2 diabetic population. PPARgamma has been identified as a key regulator of adipogenesis.
E, Iwata, I, Yamamoto, T, Motomura, S, Tsubakimori, S, Nohnen, M, Ohmoto, T, Igarashi, J, Azuma   +7 more
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[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004
Gene PPARgamma is one of the pivotal factors that influence adipocyte differentiation. It is transcriptional factor that plays a crucial role in the regulation of genes involved in lipid utilisation and storage as well as insulin action. The aim of this study was to evaluate whether PPARgamma Pro12Ala and Pro115Gln polymorphisms are connected with ...
Bozena, Bidzińska, Marek, Demissie, Urszula, Tworowska, Ryszard, Slezak, Tadeusz, Dobosz, Andrzej, Milewicz   +5 more
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Maternal PPARG Pro12Ala polymorphism is associated with infant's neurodevelopmental outcomes at 18 months of age

Early Human Development, 2015
Peroxisome proliferator activated receptors (PPARs) are ligand activated transcription factors with crucial functions in lipid homeostasis, glucose metabolism, anti-inflammatory processes, placental development, and are involved in cognitive functions and neurodegenerative diseases.
Francisco J, Torres-Espínola, Signe, Altmäe, Maria Teresa, Segura, Antonio, Jerez, Tania, Anjos, Maribel, Chisaguano, M, Carmen López-Sabater, Carmen, Entrala, Juan Carlos, Alvarez, Ahmad, Agil, Jesus, Florido, Andres, Catena, Miguel, Pérez-García, Cristina, Campoy   +13 more
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Association between ACE gene Insertion/Deletion (ACE I/D) polymorphism, PPAR-gamma Pro12Ala (Pro12Ala) polymorphism and ATPIII metabolic syndrome components in a cohort of obese subjects.

2007
Introduction: Metabolic syndrome (MetS) is defined as a cluster of risk factors for cardiovascular disease. Aim of this study was to evaluate the association between metabolic syndrome components (ATPIII) and the presence of two common polymorphisms (Pro12Ala and ACE I/D) in a cohort of obese individuals. Materials and methods: 140 subjects (M/F= 44/96)
DALLA NORA, Edoardo, PASSARO, Angelina, MARCELLO, Maria Caterina, MARI, Elisa, Volpato, S, Bolognesi, C, Bosi, C, FELLIN, Renato   +7 more
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[Association of PPARgamma2 Pro12Ala polymorphism and cognitive dysfunction in hypertension patients].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2012
To study the relationship between PPARgamma2 Pro12Ala polymorphism and cognitive function in patients with primary hypertension.This study enrolled 502 hypertensive patients of Chinese Han population from Jan 2008 to Feb 2009 in West China Hospital of Sichuan University. We collected the general data and applied the mini mental state examination (MMSE)
Yong, Peng, Xiao-jia, Luo, Xiao-ping, Chen, Long-xin, Li, Li-yan, Wan, Sen, He, Xiao-ni, Chen, Kai, Wu   +7 more
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PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy.

Current HIV research, 2010
Peroxisome proliferator-activated receptor gamma (PPARgamma) is involved in obesity and in some components of the metabolic syndrome in unselected population. To determine whether PPARgamma genetic variants are associated with the risk of developing lipodystrophy and its associated metabolic disturbances in HIV-1-infected patients treated with HAART ...
Maria, Saumoy, Sergi, Veloso, Carlos, Alonso-Villaverde, Pere, Domingo, Matilde R, Chacón, Merce, Miranda, Gerard, Aragonès, Maria Mar, Gutiérrez, Consuelo, Viladés, Joaquim, Peraire, Joan-Josep, Sirvent, Miguel, López-Dupla, Carmen, Aguilar, Cristóbal, Richart, Francesc, Vidal   +14 more
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SP436 – The Pro12Ala polymorphism of PPARG gene and OSAHS

Otolaryngology - Head and Neck Surgery, 2009
Shan-Kai Yin, Hai-Bo Shi, Jian Guan
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