Results 91 to 100 of about 5,573 (260)

Tumour‐informed workflow to use ctDNA as a biomarker for risk of recurrence in head and neck cancer patients post‐treatment

VIEW, EarlyView.
Our study presents a tumour‐informed circulating tumour DNA (ctDNA) workflow designed to enhance the detection of recurrence in head and neck cancer patients, addressing key challenges such as low ctDNA tumour fractions and tumour heterogeneity. Abstract Circulating tumour DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment
Xiaomin Huang, Paul Leo, Mhairi Clout, Lynn Fink, Jonathan Ellis, Brett G. M. Hughes, Lizbeth Kenny, Sarju Vasani, Chamindie Punyadeera   +8 more
wiley   +1 more source

Renewal bud traits as a link between whole plant traits and herbaceous species phenology

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Overwintering below‐ground buds and organs determine spring regrowth of perennial herbs in temperate regions. This effect could also manifest further in the timing and duration of plant growth and flowering and has been documented in some species and organ types ...
Renáta Schnablová, Tereza Mašková, Tomáš Koubek, Alena Bartušková, Petr Šmarda, Jitka Klimešová, Tomáš Herben   +6 more
wiley   +1 more source

No Effect of Low‐Dose Aspirin Versus Placebo as Add‐On Treatment in Bipolar Disorder—Results From a Randomised Controlled Trial (the A‐Bipolar RCT)

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Robust evidence associates immunoinflammatory dysfunction and bipolar disorder (BD), with immune dysregulation present in patients newly diagnosed with BD. This suggests that anti‐inflammatory agents, like low‐dose aspirin (LDA), might be repurposed in the treatment of early‐stage BD.
Caroline Fussing Bruun, Helle B. Krogh, Jeff Zarp, Julie Ravneberg Stokholm, Julie Lyng Forman, Kamilla Woznica Miskowiak, Annamaria Giraldi, Maj Vinberg, Maria Faurholt‐Jepsen, Lars Vedel Kessing   +9 more
wiley   +1 more source

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, EarlyView.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Effects of Access Cavity Design on the Shaping Ability and Dentine Thickness Following Canal Preparation Using XP‐Endo Shaper or Reciproc

Australian Endodontic Journal, EarlyView.
ABSTRACT This study compared the shaping ability and remaining dentine thickness in mandibular molars prepared with traditional (TradAC) or ultraconservative (UltraAC) access cavities using Reciproc or XP‐endo Shaper instruments. Thirty‐two molars were scanned with micro‐CT before and after preparation to assess canal surface, volume, untouched walls ...
Renata Muniz Alvez Cruz, Ana Flávia Almeida Barbosa, Carolina Oliveira de Lima, Ricardo Tadeu Lopes, Marco Aurélio Versiani, Emmanuel João Nogueira Leal da Silva, Luciana Moura Sassone   +6 more
wiley   +1 more source

Evaluation of markers of outcome in real-world treatment of diabetic macular edema

Eye and Vision, 2018
Objective To evaluate short-term markers of outcome in diabetic macular edema (DME). Methods Prospective interventional case series included 122 eyes of 122 patients with recently diagnosed DME.
António Campos, Elisa J Campos, Anália do Carmo, Francisco Caramelo, João Martins, João P Sousa, António Francisco Ambrósio, Rufino Silva   +7 more
doaj   +1 more source

Major Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area

Allergy, EarlyView.
This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović, Daria Trifonova, Zicheng Liu, Mirela Curin, Laszlo Schooltink, Theo Sagmeister, Christoph Grininger, Renata Kiss, Nina Gottstein, Bernd Gesslbauer, Andreas Winkler, Tea Pavkov‐Keller, Alexander Karaulov, Rudolf Valenta, Walter Keller   +14 more
wiley   +1 more source

Short-term efficacy of intravitreal conbercept in treatment-naive patients with polypoidal choroidal vasculopathy

Drug Design, Development and Therapy, 2018
Yuting Peng, Xiongze Zhang, Miaoling Li, Bing Liu, Lan Mi, Chengguo Zuo, Feng Wen State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China Introduction: To evaluate the functional and morphological ...
Peng Y, Zhang X, Li M, Liu B, Mi L, Zuo C, Wen F   +6 more
doaj  

Pro re Nata versus Bimonthly Regimen in Exudative AMD Treated with Aflibercept: 1-year Results [PDF]

, 2017
Jean-Julien Keppi, Benjamin Wolff, Laurent Castelnovo, Guillaume Michel, Claude Speeg‐Schatz, David Gaucher   +5 more
openalex   +1 more source

Manejo enfermero de la medicación psicotrópica "Pro Re Nata": Revisión bibliográfica

, 2023
Introducción:Los fármacos a demanda o “Pro Re Nata”, son aquellos fármacos empleados en situaciones específicas, independientemente de la medicación habitual. Dentro de estos, encontramos los psicotrópicos PRN usados generalmente en el paciente agitado o con insomnio. Sin embargo, esta forma de prescripciónestá asociada con un gran riesgo de morbilidad,
Campos Benedicto, Irene, Urcola Pardo, Fernando   +1 more
openaire   +1 more source