Results 61 to 70 of about 15,697,207 (237)

Dependent and Independent Time Series Errors Under Elliptically Countered Models

open access: yesEconometrics
We explore the impact of time series behavior on model errors when working under an elliptically contoured distribution. By adopting a time series approach aligned with the realistic dependence between errors under such distributions, this perspective ...
Fredy O. Pérez-Ramirez   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Average flow rate effect on the reliability of submersible electric motors of borehole pumping units in uranium mining by the in-situ leaching method

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов
Relevance. The reliability of borehole pumping units used for uranium in-situ leaching mining is largely determined by the performance of submersible electric motors.
Alexander A. Efremov   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Probabilistic modeling and numerical simulation of the three-point bending behavior of wooden beams

open access: yesResults in Materials
This paper presents a simplified yet realistic numerical model, based on a uniform probabilistic law and Monte Carlo simulations, to investigate the failure behavior of wood in static three-point bending.The proposed approach replaces the real ...
Jean De La Croix Gnappoun   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Improving the quality of hydrological forecasting by reducing the information criticality of fuzzy estimates of river runoff indicators

open access: yesВодное хозяйство России: проблемы, технологии, управление
The relevance of the study is due to the need to improve the accuracy of water runoff forecasting, which is of key importance for water resources management, hydropower engineering and flood risk prevention.
Nadezhda A. Volkova
doaj   +1 more source

Probabilistic reliability model of electrical motors in submersible well pumping units used in the uranium mining by in-situ leaching

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов
Relevance. A submersible electric motor is the most vulnerable component of an electric centrifugal pumping unit used in in-situ leaching uranium mining.
Alexander A. Yefremov   +4 more
doaj   +1 more source

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