Results 71 to 80 of about 1,653,906 (317)
Evidential Probabilities and Credences [PDF]
, 2019 Enjoying great popularity in decision theory, epistemology, and philosophy of science, Bayesianism as understood here is fundamentally concerned with epistemically ideal rationality.
Eder, Anna-Maria
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Prise de décision probabiliste spontanée chez les apprenants marocains
Annales de Didactique et de Sciences CognitivesIn our modern society, individuals are often faced with situations in which they have to make decisions spontaneously in an environment involving chance, in which the use of probability remains an adequate tool occupying an important status.
Zahid El M’Hamedi
doaj +1 more source
Chances and risks in medical risk communication
GMS German Medical Science, 2015 Communication between physicians and patients in everyday life is marked by a number of disruptive factors. Apart from specific interests, mistakes, and misunderstandings on both sides, there are main factors that contribute to the risk in risk ...
Hoffrage, Ulrich, Koller, Michael
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Notre Dame Journal of Formal Logic, 1984 The paper opens with a brief historical sketch of the many varied conceptions of the subject which have been considered. Confined to the propositional level, a logic is then presented in which the notion of probability replaces that of truth. Superficially a many-valued logic, it differs from what has heretofore been studied as many-valued logic in ...
openaire +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Market-Implied Risk-Neutral Probabilities, Actual Probabilities, Credit Risk and News
IIMB Management Review, 2011 Motivated by the credit crisis, this paper investigates links between risk-neutral probabilities of default implied by markets (e.g. from yield spreads) and their actual counterparts (e.g. from ratings).
Shashidhar Murthy
doaj +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source