Results 51 to 60 of about 2,561,356 (330)

Shaking Table Test-Based Verification of PDEM for Random Seismic Response of Anchored Rock Slopes

Applied Sciences
This study systematically verified the applicability and accuracy of the Probability Density Evolution Method (PDEM) in the probabilistic modeling of the dynamic response of anchored rock slopes under random seismic action through large-scale shaking ...
Xuegang Pan, Jinqing Jia, Lihua Zhang
doaj   +1 more source

The Linear Probability Density Function of Continuous Random Variables in the Real Number Field and Its Existence Proof

MATEC Web of Conferences, 2016
For a continuous random variable in real number field, there must be a distribution and also a probability density function of this random variable. If there is a known function with this random variable as independent variable, its image is a smooth or ...
Chen Yiyan, Li Ye
doaj   +1 more source

ON THE EVOLUTION OF THE DENSITY PROBABILITY DENSITY FUNCTION IN STRONGLY SELF-GRAVITATING SYSTEMS [PDF]

, 2013
The time evolution of the probability density function (PDF) of the mass density is formulated and solved for systems in free-fall using a simple approximate function for the collapse of a sphere. We demonstrate that a pressure-free collapse results in a
P. Girichidis, L. Konstandin, A. Whitworth, R. Klessen   +3 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Nonparametric Probability Density Function Estimation Using the Padé Approximation

Algorithms
Estimating the Probability Density Function (PDF) of observed data is crucial as a problem in its own right, and also for diverse engineering applications.
Hamid Reza Aghamiri, S. Abolfazl Hosseini, James R. Green, B. John Oommen   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Heuristic Kernel Density Estimator for Modal‑Proximity Data

Shuju Caiji Yu Chuli
Different from the classical probability density estimator construction strategies based on the Parzen window method， we propose a heuristic kernel density estimator （HKDE） based on nearest neighbor error measurement function， to improve the accuracy of ...
HE Yulin, CHEN Chunjia, HUANG Zhexue, LI Junjie, FOURNIER‑VIGER Philippe   +4 more
doaj   +1 more source

Simulated Annealing with Gaussian Probability Density Function for Transmission Expansion Planning

U.Porto Journal of Engineering, 2015
Simulated Annealing (SA) is a powerful tool for optimization problems that have several local optima. This tool has the ability to escape from a local optima accepting relatively bad solutions for a period and searching for good solutions in your ...
Phillipe Gomes
doaj   +1 more source

PROBABILITY DENSITY FUNCTIONS OF BREAKING WAVES

Coastal Engineering Proceedings, 1978
Waves in the surf zone are a highly nonlinear process which is evident by the appearance of secondary waves. The secondary waves appear as strong peaks in the period PDFs corresponding to the first harmonic of the peak of the wave spectrum. The strong first harmonic period peak is also reflected in the highly correlated height and velocity PDFs. Due to
Edward B. Thornton, George Schaeffer
openaire   +3 more sources