Results 41 to 50 of about 678,502 (291)
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Optimal Information Transfer and the Uniform Measure over Probability Space
For a quantum system with a d-dimensional Hilbert space, suppose a pure state |ψ⟩ is subjected to a complete orthogonal measurement. The measurement effectively maps |ψ⟩ to a point (p1,…,pd) in the appropriate probability simplex.
William K. Wootters
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
A joint limit theorem for periodic Hurwitz zeta-functions with algebraic irrational parameters
In the paper, a joint limit theorem for weakly convergent probability measures in ℂ r for periodic Hurwitz zeta-functions with algebraic irrational parameters satisfying certain independence conditions is obtained.
Danutė Genienė +1 more
doaj +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Value Distribution of General Dirichlet series. VI
In the paper a limit theorem in the sense of weak convergence of probability measures on the complex plane for a new class of general Dirichlet series is obtained.
A. Laurinčikas
doaj +1 more source
On how to measure the probabilities of target atom ionization and target ion back-attraction in high-power impulse magnetron sputtering [PDF]
Martin Rudolph +7 more
openalex +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

