Results 61 to 70 of about 678,502 (291)

On the Čech-Completeness of the Space of τ-Smooth Idempotent Probability Measures

open access: yesAxioms
For the set I(X) of probability measures on a compact Hausdorff space X, we propose a new way to introduce the topology by using the open subsets of the space X.
Ljubiša D. R. Kočinac   +2 more
doaj   +1 more source

On Joint Distribution of General Dirichlet Series

open access: yesNonlinear Analysis, 2003
In the paper a joint limit theorem in the sense of the weak convergence in the space of meromorphic functions for general Dirichlet series is proved under weaker conditions as in [1].
J. Genys, A. Laurinčikas
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Weighting order and disorder on complexity measures

open access: yesJournal of Taibah University for Science, 2017
The initial ideas regarding measuring complexity appeared in computer science, with the concept of computational algorithms. As a consequence, the equivalence between algorithm complexity and informational entropy was shown.
José Roberto C. Piqueira
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Partitioning General Probability Measures

open access: yesThe Annals of Probability, 1987
Consider n probability measures \(\mu_ 1,...,\mu_ n\) on the same measurable space. It is the aim to split the whole sample set \(\Omega\) into n measurable parts \(A_ 1,...,A_ n\) such that \(A_ j\) has nearly the same probability for each distribution. Here the author considers the case when the atoms have not too large mass.
openaire   +3 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Probability measure monad on the category of ultrametric spaces

open access: yesApplied General Topology, 2008
The set of all probability measures with compact support on an ultrametric space can be endowed with a natural ultrametric. We show that the functor of probability measures with finite supports (respectively compact supports) forms a monad in the ...
O.B. Hubal, M.M. Zarichnyi
doaj   +1 more source

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