Results 51 to 60 of about 1,935 (215)

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

open access: yesAdvanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu   +5 more
wiley   +1 more source

Regulating Solvent‐Separated Ion Pairs to Control Polysulfide Redox for Fast and Stable Room‐Temperature Na‐S Batteries

open access: yesAdvanced Science, EarlyView.
A local high‐concentration electrolyte with tailored solvent‐separated ion pairs is pioneered to design for room‐temperature sodium‐sulfur batteries. This electrolyte allows sparingly dissolved polysulfides and localizes them onto reactive interfaces for liquid‐solid conversion.
Xiang‐Long Huang   +11 more
wiley   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli   +12 more
wiley   +1 more source

Ionic Highways under Multivariate‐Coupled Strategies: Ultrahigh Power Generation from Industrial Waste Liquors Using Robust COF Membranes

open access: yesAdvanced Science, EarlyView.
This study presents a multivariate‐coupled strategy to fabricate TB‐COF membranes with tunable charge density via uniformly distributed Bpy groups, enabling efficient ion transport and energy harvesting. The robust β‐ketoenamine‐linked structure ensures stability, achieving power outputs of 53.08 W m−2 (pH 4), 190.52 W m−2 (low‐grade heat), and 258.81 ...
Hongyan Qi   +13 more
wiley   +1 more source

Magneto‐X Effects in Magnetic Soft Materials and Their Applications

open access: yesAdvanced Science, EarlyView.
This review systematically explores magnetic soft materials (MSMs), a novel class of composites that transform under magnetic fields. It catalogs fundamental “Magneto‐X” effects, classifies materials by their matrix and magnetic fillers, and highlights transformative applications in soft robotics, biomedical devices, flexible electronics, etc. Finally,
Ziyin Xiang   +5 more
wiley   +1 more source

On the Risk of Ruin in a SIS Type Epidemic. [PDF]

open access: yesMethodol Comput Appl Probab, 2022
Lefèvre C, Simon M.
europepmc   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

On The Randomized Schmitter Problem. [PDF]

open access: yesMethodol Comput Appl Probab, 2022
Albrecher H, Araujo-Acuna JC.
europepmc   +1 more source

Multi‐Physical Field Modulated P‐Bit Device Based on VO2 Thin Film

open access: yesAdvanced Science, EarlyView.
We have proposed a VO2‐based P‐bit device where synergistic multi‐physical field modulation enables real‐time tunability of randomness. Besides introducing a new phase‐change material‐based device approach for high‐performance P‐bits, this study also demonstrates a synergistic multi‐physical field modulation strategy that opens new opportunities for ...
Bowen Sun   +10 more
wiley   +1 more source

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