Results 81 to 90 of about 1,787,476 (292)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Optimising species detection probability and sampling effort in lake fish eDNA surveys [PDF]

Metabarcoding and Metagenomics
Environmental DNA (eDNA) metabarcoding is transforming biodiversity monitoring in aquatic environments. Such an approach has been developed and deployed for monitoring lake fish communities in Great Britain, where the method has repeatedly shown a ...
Graham S. Sellers, Christopher L. Jerde, Lynsey R. Harper, Marco Benucci, Cristina Di Muri, Jianlong Li, Graeme Peirson, Kerry Walsh, Tristan Hatton-Ellis, Willie Duncan, Alistair Duguid, Dave Ottewell, Nigel Willby, Alan Law, Colin W. Bean, Ian J. Winfield, Daniel S. Read, Lori Lawson Handley, Bernd Hänfling   +18 more
doaj   +3 more sources

New estimators for estimating population total: an application to water demand in Thailand under unequal probability sampling without replacement for missing data. [PDF]

PeerJ, 2022
Ponkaew C, Lawson N.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Elimination of redundancy in telemetered data [PDF]

, 1970
Procedure for estimating the intensity of a Poisson process can be readily programmed for a digital computer, and does not require an a priori probability space.
Vu-Son, C.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Critical Analysis of Sampling Designs in Human Geography Research by Focusing on Selection Bias in Probability Samples

تحقيقات جغرافيايی, 2018
Using of words " probability and random" has such a special meaning and in research sampling method from the point of view of research method principles, it means respecting the principles and rules of sampling theory and lack of selection bias in ...
Masoud Safaei Pour, Alireza Rahimi Chamkhani   +1 more
doaj  

Best linear unbiased estimation for varying probability with and without replacement sampling

Special Matrices, 2019
When sample survey data with complex design (stratification, clustering, unequal selection or inclusion probabilities, and weighting) are used for linear models, estimation of model parameters and their covariance matrices becomes complicated.
Haslett Stephen
doaj   +1 more source

Line Sampling with Probability Proportional to The Geometrical Average Area Per Tree in The Stand [PDF]

Floresta e Ambiente
The study proposes a sampling method, termed the probability proportional to the average geometric area of occupation, method in which a set of trees along a row is selected as the sampling unit with a probability proportional to the geometrical average ...
Sylvio Péllico Netto, Alexandre Behling, Ataides Marinheski Filho, Ângelo Augusto Ebling, Claiton Nardini   +4 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source