Results 61 to 70 of about 246,472 (288)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Implementasi teknik Probing-Prompting Scaffolding untuk meningkatkan kemampuan pemecahan masalah dan kemandirian belajar matematis siswa [PDF]
, 2018 Penelitian ini bertujuan mengetahui peningkatan kemampuan pemecahan masalah siswa yang menerima pembelajaran Probing-Prompting Scaffolding terhadap 93 siswa. Penelitian ini menggunakan metode quasi eksperimen. Instrumen yang digunakan yaitu instrumen tes
Fatimah, Rizki Nuraini
core +1 more source
Penerapan Model Probing Prompting terhadap Hasil Belajar IPS Siswa Kelas IV SD [PDF]
Tujuan penelitian ini untuk mengetahui ketuntasan hasil belajar setelah diterapkan model pembelajaran probing prompting dalam pembelajaran IPS siswa kelas IV SD Negeri 02 Lubuklinggau.
Hamdan, Hamdan +2 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Pengaruh Penggunaan Model Pembelajaran Probing- Prompting Terhadap Hasil Belajar Siswa Pada Mata Pelajaran Matematika [PDF]
, 2017 Penelitian ini bertujuan untuk mengetahui ada tidaknya pengaruh penggunaan model pembelajaran probing-prompting terhadap hasil belajar siswa dan mengetahui sikap siswa terhadap pembelajaran matematika yang menggunakan model pembelajaran Probing-prompting.
Mansur, Mansur +1 more
core
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Unnes Journal of Mathematics Education, 2017 The purpose of this research was to know that the learning model ProbingPrompting with Scaffolding strategy effective on the mathematic creative thinking ability and enthusiasm.
Miftah Hafidz Alfian +2 more
doaj +1 more source
MENINGKATKAN PENALARAN SISWA TERHADAP SOAL MATEMATIKA BERBASIS CERITA MELALUI TEKNIK PROBING-PROMPTING PADA MATERI BANGUN RUANG SISI DATAR BAGI SISWA KELAS 8 DI SMP NEGERI 2 KEMRANJEN [PDF]
, 2015 Tujuan penelitian ini adalah untuk meningkatkan penalaran siswa pada soal matematika berbasis cerita, melalui teknik probing-prompting pada materi bangun ruang sisi datar bagi siswa kelas 8 di SMP Negeri 2 Kemranjen.
Neni, Sri
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source