Results 161 to 170 of about 130,832 (304)

Metabolite profiling of human‐originated Lachnospiraceae at the strain level

iMeta, Volume 1, Issue 4, December 2022., 2022
The human‐originated Lachnospiraceae biobank included 77 species was constructed. In vitro metabolite profiling of 110 Lachnospiraceae strains yielded 242 metabolites of 17 categories. Many Lachnospiraceae strains produce short‐chain fatty acids, and Agathobacter rectalis strain Lach‐101 and Coprococcus comes strain NSJ‐173 are the top two butyric acid
Rashidin Abdugheni, Wen‐Zhao Wang, Yu‐Jing Wang, Meng‐Xuan Du, Feng‐Lan Liu, Nan Zhou, Cheng‐Ying Jiang, Chang‐Yu Wang, Linhuan Wu, Juncai Ma, Chang Liu, Shuang‐Jiang Liu   +11 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Targeting keystone species helps restore the dysbiosis of butyrate‐producing bacteria in nonalcoholic fatty liver disease

iMeta, Volume 1, Issue 4, December 2022., 2022
In this study, we applied an algorithm to the keystone species identification in the gut microbiome, based on current causal inference theories and the dynamic intervention simulation. We identified the nonalcoholic steatohepatitis (NASH) keystone species combination, represented by Porphyromonas loveana, Alistipes indistinctus, and Dialister ...
Dingfeng Wu, Lei Liu, Na Jiao, Yida Zhang, Li Yang, Chuan Tian, Ping Lan, Lixin Zhu, Rohit Loomba, Ruixin Zhu   +9 more
wiley   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

Dietary fiber chemical structure determined gut microbiota dynamics

iMeta, Volume 1, Issue 4, December 2022., 2022
The monosaccharide composition and glycosidic bond configuration determine the CAZyme that could hydrolyze it. Thus, bacteria encoding specific CAZyme utilize different structured dietary fibers. Compounded with bacterial interaction, gut microbiota dynamics is synergistically modulated.
Xin Meng, Jun Zheng, Fengqiao Wang, Jie Zheng, Dong Yang   +4 more
wiley   +1 more source

Influence of a Probiotic on Productivity, Meat Components, Lipid Metabolism, Caecal Flora and Metabolites, and Raising Environment in Broiler Production

, 1999
Tsuyoshi Endo, Masuo Nakano
openalex   +2 more sources

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

SHORT COURSE ANTIBIOTICS WITH PROBIOTICS FOR CLOSTRIDIUM FOR CLOSTRIDIUM DIFFICILE COLITIS IN IMMUNOCOMPROMISED PATIENTS

, 1997
David R. Mack, Minnie Abromowitch, L Ramev, Rosemary J. Young, Jon A. Vanderhoof   +4 more
openalex   +1 more source

The Role of Probiotic Cultures in the Control of Gastrointestinal Health [PDF]

, 2000
Rial D. Rolfe
openalex   +1 more source

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source