Results 211 to 220 of about 168,238 (306)
Gut microbiota- and probiotic-derived bioactive metabolites: mechanisms, evidence, and therapeutic potential in metabolic disorders. [PDF]
Akpor OB, Ajinde AO.
europepmc +1 more source
By shifting from highly variable taxonomic abundance to conserved ecological network topologies, our Dual‐Stream Graph Attention Network (DS‐GAT‐CP) resolves the “abundance paradox,” enabling highly accurate and cross‐regionally robust non‐invasive screening for Type 2 Diabetes. ABSTRACT Gut microbiome‐based machine learning models for Type 2 Diabetes (
Changjian Wu +4 more
wiley +1 more source
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang +10 more
wiley +1 more source
Gut Microbiome Disruption in Traumatic Brain Injury and Therapeutic Potential of Probiotics: A Systematic Review and Meta-Analysis. [PDF]
Khan ZA +7 more
europepmc +1 more source
Benchmarking gut microbiome indices within and across populations
We compared 10 widely used gut microbiome indices in 12,561 American Gut Project participants and 10 external cohorts, testing how well each distinguished people with healthy lifestyles, responded to 79 environmental factors, and associated with 14 chronic conditions. No single index performed best on all three tasks.
Yu Sun +6 more
wiley +1 more source
Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao +10 more
wiley +1 more source

