Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng +15 more
wiley +1 more source
Feline-Derived <i>Ligilactobacillus agilis</i> ZY25 and <i>Ligilactobacillus salivarius</i> ZY35 Alleviate <i>Enteropathogenic Escherichia coli</i>-Induced Intestinal Injury and Microbial Dysbiosis in Mice. [PDF]
Wang W +9 more
europepmc +1 more source
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang +13 more
wiley +1 more source
Probiotic yeast engineers a protective biofilm environment to enhance bioremediation and seahorse health in aquaculture. [PDF]
Yao Y +7 more
europepmc +1 more source
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley +1 more source
Multi-Strain Probiotic and Bee Pollen Supplementation Attenuates CCl<sub>4</sub>-Induced Altered Intestinal Tight Junctions in Rodents. [PDF]
Alsayari N +4 more
europepmc +1 more source
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Combined Addition of Microalgae and Probiotic Enhances Bacterial Community Network Stability, Water Quality, and Fish Growth in <i>Micropterus salmoides</i> Aquaculture. [PDF]
Xu H +10 more
europepmc +1 more source
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu +6 more
wiley +1 more source
Potent Probiotic Yeast <i>Saccharomyces cerevisiae</i> TBRC 3616: Production Development for Food and Feed Applications. [PDF]
Antimanon S +10 more
europepmc +1 more source

