Results 281 to 290 of about 263,057 (342)

Role of vulvovaginal infection in women with short cervix: An observational clinical trial

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Short cervix (SC) and vulvovaginal infections, such as bacterial vaginosis (BV) and vulvovaginal candidosis (VVC), are known risk factors for preterm birth (PTB). The objective of this study was to investigate whether the combined presence of SC and vulvovaginal infections further elevates the risk of PTB.
Fanny Mikula   +5 more
wiley   +1 more source

A Dual Action of Everolimus in Ulcerative Colitis: Blocking CLEC4E‐Driven Inflammation and Remodeling the Gut Microbiota‐Metabolite Axis

open access: yesiMetaMed, EarlyView.
Graphical abstract of the major mechanisms of Everolimus in ulcerative colitis: Everolimus, a selective mTORC1 inhibitor, protects against ulcerative colitis through a dual mechanism. First, Eve directly suppresses CLEC4E/Syk/NF‐κB signaling, thereby reducing pro‐inflammatory cytokine production and preserving intestinal barrier integrity.
Jing Chen   +6 more
wiley   +1 more source

Early matrine intervention of gut microbiota for type 2 diabetes prevention

open access: yesiMetaOmics, EarlyView.
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun   +4 more
wiley   +1 more source

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