Results 71 to 80 of about 253,133 (338)

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

A Smart and Highly Porous Hydrogel for Diabetic Wound Healing

Advanced Materials Interfaces, EarlyView.
A novel hydrogel comprising a dual‐crosslinked network of Poly(N‐isopropylacrylamide) (PNIPAM) and Gum Arabic (GA) with superior mechanical and anti‐inflammatory properties is designed for advanced diabetic wound healing. Abstract Conventional hydrogels often suffer from poor mechanical strength, limited bioactivity, and uncontrolled therapeutic ...
Nouf Al Saleh, Jinrong Wang, Danyang Chen, Eman Ageely, Shuroug Al Bihan, Mohamed M. Abdelghafour, Rukhma Javaid, Ayeesha Mujeeb, Nader S Al‐Kenani, Niveen M. Khashab   +9 more
wiley   +1 more source

High-throughput workflow for cultivation and characterization of gut microbiota strains with anti-inflammatory properties and metabolite signature associated with gut-brain communication

Scientific Reports
The gut microbiota is deeply interconnected with the brain, a phenomenon often referred to as the gut-brain axis. Dysfunction in the microbiota-gut-brain axis can cause various neurological and psychiatric disorders associated with chronic inflammation ...
Jelena Đokić, Miroslav Dinić, Svetlana Soković Bajić, Aleksandar Bisenić, Hristina Mitrović, Stefan Jakovljević, Dušan Radojević, Emilija Brdarić, Jovanka Lukić, Milica Živković, Maja Tolinački, Amarela Terzić-Vidojević, Nataša Golić   +12 more
doaj   +1 more source

Methods to Evaluate Bacterial Motility and Its Role in Bacterial–Host Interactions

Microorganisms, 2022
Bacterial motility is a widespread characteristic that can provide several advantages for the cell, allowing it to move towards more favorable conditions and enabling host-associated processes such as colonization.
Victoria Palma, María Soledad Gutiérrez, Orlando Vargas, Raghuveer Parthasarathy, Paola Navarrete   +4 more
doaj   +1 more source

Utilization of Pyrosequencing to Monitor the Microbiome Dynamics of Probiotic Treated Poultry (Gallus gallus domesticus) during Downstream Poultry Processing [PDF]

, 2017
Antibiotic growth promoters that have been historically employed to control pathogens and increase the rate of animal development for human consumption are currently banned in many countries.
Bray, Joey, Clack, Beatrice, Guttala, Vamsy Priya, Medrano, Enrique G.   +3 more
core   +3 more sources

Safety of probiotics [PDF]

Clinical and Translational Allergy, 2011
Probiotics are used by millions of people for their documented or anticipated health benefits. They usu-ally belong to the genera lactobacilli and bifidobacteria and are part of the normal flora. They have been studied in a wide variety of diseases and in the prevention of inflammatory and infectious dis-eases.
openaire   +3 more sources

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

Advanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen, Libing Huang, Lei Ren, Miao Wang   +3 more
wiley   +1 more source

Investigating the efficacy of an exopolysaccharide (EPS)‐producing strain Lactiplantibacillus plantarum L75 on oat silage fermentation at different temperatures

Microbial Biotechnology
This study investigates the effectiveness of an exopolysaccharide (EPS)‐producing strain (Lactiplantibacillus plantarum L75) alone or in combination with Saccharomyces cerevisiae on the fermentation characteristics, antioxidant capacities and microbial ...
Rina Su, Ying Liang, Hu Chen, Neha Sheoran, Wencan Ke, Jie Bai, Mengya Jia, Jie Zhu, Qiang Li, Qi Liu, Xiaojun Chen, Xusheng Guo   +11 more
doaj   +1 more source

Lignocellulose conversion of ensiled Caragana korshinskii Kom. facilitated by Pediococcus acidilactici and cellulases

Microbial Biotechnology, 2023
To explore the biofuel production potential of Caragana korshinskii Kom., Pediococcus acidilactici and an exogenous fibrolytic enzyme were employed to investigate the fermentation profile, structural carbohydrates degradation, enzymatic saccharification ...
Yixin Zhang, Musen Wang, Samaila Usman, Fuhou Li, Jie Bai, Jiayao Zhang, Xusheng Guo   +6 more
doaj   +1 more source

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. [PDF]

, 2019
On December 17, 2018, the North American branch of the International Life Sciences Institute (ILSI North America) convened a workshop "Can We Begin to Define a Healthy Gut Microbiome Through Quantifiable Characteristics?" with >40 invited academic ...
Antonopoulos, Armitage, AVA, Singapore, Azad, Backhed, Barbara O Schneeman, Beaton, Beukers, Bindels, Bindels, Borewicz, Brazilian Health Regulatory Agency (ANVISA), Buddington, Cammarota, Campbell-Lendrum, Cantarel, Caporaso, Carlson, Cindy Davis, Claire M Fraser, Costea, Cummings, Curtis Huttenhower, Damen, Dao, David, David, Davis, Davoren, Desai, Deschasaux, Dethlefsen, De Preter, Earle, EFSA, EFSA, Eloe-Fadrosh, Esaiassen, European Commission, European Commission, Falony, FAO and WHO, FAO and WHO, FDA, FDA, FDA, FDA, FDA, FDA, FDA, FDA, FDA-NIH Biomarker Working Group, Fedacko, Fei, Ferretti, Fischbach, Flaherman, Flint, Forbes, Foster, Fragiadakis, Francois, François, François, Gibson, Government of Canada, Gregory, Gupta, Hadizadeh, He, Health Canada, Health Canada, Health Canada, Health Canada, Health Canada, Health Canada, Hermansson, Hildebrand, Ho, Holmes, Holmes, Holscher, Insel, Jacobsen, Jakobsson, Jangi, Janssens, Japan Consumer Affairs Agency, Japan Consumer Affairs Agency, Japan Ministry of Health, Labour, and Welfare, Japan Ministry of Health, Labour, and Welfare, Jens Walter, Jones, Kennedy, Koenig, Korpela, Kristensen, Kristin Verbeke, Kritchevsky, Krumbeck, Lahti, Lam, Langdon, Lawley, La Fata, Leiby, Lim, Lloyd-Price, Lohner, Lozupone, Makki, Maldonado-Gómez, Marcobal, Marie E Latulippe, Martin, Martinez, Martínez, Martínez, Martínez, Matamoros, McBurney, McBurney, McBurney, McFarland, Michael I McBurney, Miller, MOH Malaysia, MOH Malaysia, MOPH Thailand, Mould, Mueller, NDAC, Palleja, Perez-Muñoz, Rattanaprasert, Roager, Robb, Rothschild, Round, Russell, Rutishauser, Saxelin, Schloissnig, Schlomann, Schneeberger, Schroeder, Snijder, Song, Sonnenburg, Sonnenburg, Sprockett, Sundin, Surana, Tanemura, Tannock, Taverniti, The Human Microbiome Project Consortium, Tremlett, Trowell, Vandeputte, Vangay, Vatanen, Vellend, Venkataraman, Venkataraman, Voigt, von Wintzingerode, Walter, Wan, Wang, Watson, Wedekind, Windey, Windey, Windey, Wong, Wu, Yassour   +177 more
core   +2 more sources