Results 41 to 50 of about 4,574,423 (281)

Quantum algorithms for hidden nonlinear structures

, 2007
Attempts to find new quantum algorithms that outperform classical computation have focused primarily on the nonabelian hidden subgroup problem, which generalizes the central problem solved by Shor's factoring algorithm.
Childs, Andrew M., Schulman, Leonard J., Vazirani, Umesh V.   +2 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Commentary: JWST near-infrared detector degradation— finding the problem, fixing the problem, and moving forward

AIP Advances, 2012
The James Webb Space Telescope (JWST) is the successor to the Hubble Space Telescope. JWST will be an infrared-optimized telescope, with an approximately 6.5 m diameter primary mirror, that is located at the Sun-Earth L2 Lagrange point.
Bernard J. Rauscher, Carl Stahle, Robert J. Hill, Matthew Greenhouse, James Beletic, Sachidananda Babu, Peter Blake, Keith Cleveland, Emmanuel Cofie, Bente Eegholm, C. W. Engelbracht, Donald N. B. Hall, Alan Hoffman, Basil Jeffers, Christine Jhabvala, Randy A. Kimble, Stanley Kohn, Robert Kopp, Don Lee, Henning Leidecker, Don Lindler, Robert E. McMurray Jr., Karl Misselt, D. Brent Mott, Raymond Ohl, Judith L. Pipher, Eric Piquette, Dan Polis, Jim Pontius, Marcia Rieke, Roger Smith, W. E. Tennant, Liqin Wang, Yiting Wen, Christopher N. A. Willmer, Majid Zandian   +35 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A systematic literature review of the speculative design process and a proposed framework for speculative design

Design Science
Speculative design is widely used in research contexts across multiple disciplines, emphasising problem-finding over problem-solving, and involves methods for exploring possibilities that challenge ingrained assumptions. This systematic literature review
David Cardenas Cordova, Nick Kelly, Leo Rezayan   +2 more
doaj   +1 more source

A Novel Approach to Finding Near-Cliques: The Triangle-Densest Subgraph Problem [PDF]

, 2014
Many graph mining applications rely on detecting subgraphs which are near-cliques. There exists a dichotomy between the results in the existing work related to this problem: on the one hand the densest subgraph problem (DSP) which maximizes the average ...
Tsourakakis, Charalampos E.
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Serendipitous Shoemaker: Creativity and Passion in Participant Selection

Forum: Qualitative Social Research, 2013
The purpose of this article is to offer a particular perspective on creativity and to relate this perspective to how a participant was selected for a qualitative study.
James A. Bernauer
doaj  

THE PROBLEM OF FINDING A METHODOLOGICAL BASIS FOR STUDYING THE HISTORY OF RUSSIA

Sovremennye Issledovaniâ Socialʹnyh Problem, 2023
The article formulates the problem of finding a methodological basis for understanding the history of Russia. Modern historical cognition needs close interaction with the philosophy of history, which is designed to give a logical form to the diverse ...
Marina Yu. Neronova, Alexander V. Neronov   +1 more
doaj   +1 more source

Wide baseline stereo matching with convex bounded-distortion constraints

, 2015
Finding correspondences in wide baseline setups is a challenging problem. Existing approaches have focused largely on developing better feature descriptors for correspondence and on accurate recovery of epipolar line constraints.
Amir, Tal, Basri, Ronen, Galun, Meirav, Hassner, Tal, Lipman, Yaron   +4 more
core   +1 more source