Results 1 to 10 of about 16,116 (276)

Procainamide Inhibits DNA Methylation and Alleviates Multiple Organ Dysfunction in Rats with Endotoxic Shock [PDF]

PLoS ONE, 2016
Excessive inflammatory and oxidative stress lead to circulatory failure, multiple organ dysfunction, and high mortality in patients with sepsis. Microbial infection-induced DNA hypermethylation is associated with the augmentation of inflammation and ...
Ching-Hui Shen, Shuk-Man Ka, Yung-Lung Chang   +2 more
exaly   +5 more sources

Influence of microplastics on the toxicity of the pharmaceuticals procainamide and doxycycline on the marine microalgae Tetraselmis chuii

Aquatic Toxicology, 2018
Joana C Prata, Lúcia Guilhermino
exaly   +3 more sources

Oral procainamide as pharmacological treatment of recurrent and refractory ventricular tachyarrhythmias: A single-center experience [PDF]

Heart Rhythm O2, 2021
Background: Antiarrhythmic therapy for recurrent ventricular arrhythmias in patients who have undergone catheter ablation, and in whom amiodarone and/or beta-blockers were ineffective or contraindicated, is a controversial issue.
Mauro Toniolo, MD, Daniele Muser, MD, Giulia Grilli, MD, Massimo Burelli, MD, Luca Rebellato, MD, Elisabetta Daleffe, MD, Domenico Facchin, MD, Massimo Imazio, MD   +7 more
doaj   +2 more sources

Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

Journal of Pharmaceutical Analysis, 2017
Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug.
Sharanappa T Nandibewoor, Shivamurti A Chimatadar   +1 more
exaly   +4 more sources

Procainamide–SAHA Fused Inhibitors of hHDAC6 Tackle Multidrug-Resistant Malaria Parasites

Journal of Medicinal Chemistry, 2021
Epigenetic post-translational modifications are essential for human malaria parasite survival and progression through its life cycle. Here, we present new functionalized suberoylanilide hydroxamic acid (SAHA) derivatives that chemically combine the pan ...
Flore Nardella, Ludovic Halby, Corentin Bon   +2 more
exaly   +3 more sources

Non-covalent interaction, adsorption characteristics and solvent effect of procainamide anti-arrhythmias drug on silver and gold loaded silica surfaces: SERS spectroscopy, density functional theory and molecular docking investigations

RSC Advances, 2023
First-principle calculations were systematically carried out to explore the structural and electronic properties of the non-covalent interaction of procainamide (PA) anti-arrhythmias drug molecules on silver-loaded and gold-loaded silica nanostructures ...
S Muthu
exaly   +4 more sources

Bolus Intravenous Procainamide in Patients with Frequent Ventricular Ectopics during Cardiac Magnetic Resonance Scanning: A Way to Ensure High Quality Imaging

Diagnostics, 2021
Acquiring high-quality cardiac magnetic resonance (CMR) images in patients with frequent ventricular arrhythmias remains a challenge. We examined the safety and efficacy of procainamide when administered on the scanner table prior to CMR scanning to ...
Chrysovalantou Nikolaidou, Konstantinos Kouskouras, Nikolaos Fragakis, Vassilios P. Vassilikos, Haralambos Karvounis, Theodoros D. Karamitsos   +5 more
doaj   +2 more sources

Fever, Syncope, and the Brugada Dilemma: Navigating the Complexities of ICD Decision-Making in an Atypical Presentation [PDF]

Case Reports in Cardiology
Brugada syndrome (BrS) is a rare inherited cardiac channelopathy associated with ventricular arrhythmias and sudden cardiac death (SCD), often in individuals with structurally normal hearts.
Lorna Devkota, Michael Hoffer-Hawlik, Felix Yang, Albert S. Jung   +3 more
doaj   +2 more sources

The Pharmacology and Clinical Use of Lidocaine and Procainamide [PDF]

, 1973
Both procainamide and lidocaine are useful for acutely treating cardiac arrhythmias, and procainamide can be useful in chronic antiarrhythmic regimens.
J. Thomas Bigger, Elsa‐Grace V. Giardina   +1 more
openalex   +3 more sources

Synthesis of 4-Amino-N-[2 (diethylamino)Ethyl]Benzamide Tetraphenylborate Ion-Associate Complex: Characterization, Antibacterial and Computational Study

Molecules, 2023
The 4-amino-N-[2 (diethylamino) ethyl] benzamide (procainamide)-tetraphenylborate complex was synthesized by reacting sodium tetraphenyl borate with 4-amino-N-[2 (diethylamino) ethyl] benzamide, chloride salt, and procainamide in deionized water at room ...
Gamal A. E. Mostafa, Ahmed H. Bakheit, Mohamed H. Al-Agamy, Rashad Al-Salahi, Essam A. Ali, Haitham Alrabiah   +5 more
doaj   +1 more source