Results 1 to 10 of about 5,140 (161)

Ventricular Tachycardia due to an Overdose of Tibetan Drugs: A Case Report of Aconitine Poisoning. [PDF]

open access: yesClin Case Rep
ABSTRACT Tibetan medicine enjoys a high recognition among Tibetans. Many Tibetan hospitals and medicine shops are dedicated to related research and prescribe Tibetan drugs to patients. Overdose intake of aconite‐containing Tibetan drugs might cause severe poisoning manifesting malignant ventricular arrhythmias.
Liu P, Niu M, Zhang X, Han H.
europepmc   +2 more sources

Hybrid Molecules as Efficient Drugs against Multidrug-Resistant Malaria Parasites. [PDF]

open access: yesChemMedChem
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Robert A   +6 more
europepmc   +2 more sources

Selective hydrogenation of nitro compounds to amines by coupled redox reactions over a heterogeneous biocatalyst. [PDF]

open access: yesNat Commun
Cleaner synthesis of amines remains a key challenge in organic chemistry because of their prevalence in pharmaceuticals, agrochemicals and synthetic building blocks. Here, we report a different paradigm for chemoselective hydrogenation of nitro compounds
Sokolova D   +7 more
europepmc   +2 more sources

Procainamide Inhibits DNA Methylation and Alleviates Multiple Organ Dysfunction in Rats with Endotoxic Shock. [PDF]

open access: yesPLoS ONE, 2016
Excessive inflammatory and oxidative stress lead to circulatory failure, multiple organ dysfunction, and high mortality in patients with sepsis. Microbial infection-induced DNA hypermethylation is associated with the augmentation of inflammation and ...
Chih-Chin Shih   +8 more
doaj   +1 more source

Synthesis of 4-Amino-N-[2 (diethylamino)Ethyl]Benzamide Tetraphenylborate Ion-Associate Complex: Characterization, Antibacterial and Computational Study

open access: yesMolecules, 2023
The 4-amino-N-[2 (diethylamino) ethyl] benzamide (procainamide)-tetraphenylborate complex was synthesized by reacting sodium tetraphenyl borate with 4-amino-N-[2 (diethylamino) ethyl] benzamide, chloride salt, and procainamide in deionized water at room ...
Gamal A. E. Mostafa   +5 more
doaj   +1 more source

Bolus Intravenous Procainamide in Patients with Frequent Ventricular Ectopics during Cardiac Magnetic Resonance Scanning: A Way to Ensure High Quality Imaging

open access: yesDiagnostics, 2021
Acquiring high-quality cardiac magnetic resonance (CMR) images in patients with frequent ventricular arrhythmias remains a challenge. We examined the safety and efficacy of procainamide when administered on the scanner table prior to CMR scanning to ...
Chrysovalantou Nikolaidou   +5 more
doaj   +1 more source

Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. [PDF]

open access: yesPLoS ONE, 2016
Overt systemic inflammatory response is a predisposing mechanism for infection-induced skeletal muscle damage and rhabdomyolysis. Aberrant DNA methylation plays a crucial role in the pathophysiology of excessive inflammatory response.
Chih-Chin Shih   +6 more
doaj   +1 more source

Effects of 1α,25-Dihydroxyvitamin D3 on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in Rats with PBPK Modeling Approach

open access: yesPharmaceutics, 2021
In this study, possible changes in the expression of rat organic cationic transporters (rOCTs) and rat multidrug and toxin extrusion proteins (rMATEs) following treatment with 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) were investigated.
Anusha Balla   +6 more
doaj   +1 more source

Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021
The importance of relieving paroxysms of fibrillation and atrial flutter is determined by a huge number of patients suffering from this pathology and its recurrent course.Objective: To create an algorithm for the treatment of patients with atrial ...
A. G. Pronin   +2 more
doaj   +1 more source

Development of multifocal atrial tachycardia in a patient using aminophylline -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
An 82-year-old female, with left femoral neck fracture was scheduled for left hip hemiarthroplasty, under spinal anaesthesia. She had been suffering from diabetes, hypertension, lung cancer and was previously treated with IV aminophylline for respiratory
Lee Kyoung Kim   +2 more
doaj   +1 more source

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