Results 11 to 20 of about 16,116 (276)

Effects of 1α,25-Dihydroxyvitamin D3 on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in Rats with PBPK Modeling Approach

open access: yesPharmaceutics, 2021
In this study, possible changes in the expression of rat organic cationic transporters (rOCTs) and rat multidrug and toxin extrusion proteins (rMATEs) following treatment with 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) were investigated.
Anusha Balla   +6 more
doaj   +2 more sources

Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. [PDF]

open access: yesPLoS ONE, 2016
Overt systemic inflammatory response is a predisposing mechanism for infection-induced skeletal muscle damage and rhabdomyolysis. Aberrant DNA methylation plays a crucial role in the pathophysiology of excessive inflammatory response.
Chih-Chin Shih   +6 more
doaj   +2 more sources

Comparison of 2-Aminobenzamide, Procainamide and RapiFluor-MS as Derivatizing Agents for High-Throughput HILIC-UPLC-FLR-MS N-glycan Analysis

open access: yesFrontiers in Chemistry, 2018
Rising awareness of the universal importance of protein N-glycosylation governs the development of further advances in N-glycan analysis. Nowadays it is well known that correct glycosylation is essential for proper protein function, which emanates from ...
Toma Keser   +4 more
doaj   +2 more sources

Chemoenzymatically Synthesized O-Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context. [PDF]

open access: yesAngew Chem Int Ed Engl
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhang Z   +5 more
europepmc   +3 more sources

Development of multifocal atrial tachycardia in a patient using aminophylline -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
An 82-year-old female, with left femoral neck fracture was scheduled for left hip hemiarthroplasty, under spinal anaesthesia. She had been suffering from diabetes, hypertension, lung cancer and was previously treated with IV aminophylline for respiratory
Lee Kyoung Kim   +2 more
doaj   +1 more source

Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021
The importance of relieving paroxysms of fibrillation and atrial flutter is determined by a huge number of patients suffering from this pathology and its recurrent course.Objective: To create an algorithm for the treatment of patients with atrial ...
A. G. Pronin   +2 more
doaj   +1 more source

The role of the mobile proton in fucose migration [PDF]

open access: yes, 2019
Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent ...
Helden, Gert von   +7 more
core   +1 more source

Laparoscopic Cholecystectomy in a Young Female With Wolff-Parkinson-White Syndrome: Anesthetic Implications and Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT This case highlights that, with thorough preoperative assessment, continuous careful intraoperative monitoring, precise anesthetic selection, and multidisciplinary coordination, patients with incidentally detected Wolff–Parkinson–White (WPW) syndrome can safely undergo laparoscopic cholecystectomy under general anesthesia, demonstrating that ...
Bhatta S, Pandit S.
europepmc   +2 more sources

Identification of novel DNA methylation inhibitors via a two-component reporter gene system

open access: yesJournal of Biomedical Science, 2011
Background Targeting abnormal DNA methylation represents a therapeutically relevant strategy for cancer treatment as demonstrated by the US Food and Drug Administration approval of the DNA methyltransferase inhibitors azacytidine and 5-aza-2 ...
Chen Ching-Shih   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy