Frontiers in Chemistry, 2018 Rising awareness of the universal importance of protein N-glycosylation governs the development of further advances in N-glycan analysis. Nowadays it is well known that correct glycosylation is essential for proper protein function, which emanates from ...
Toma Keser +4 more
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Spectrophotometric determination of procainamide hydrochloride using sodium periodate
Arabian Journal of Chemistry, 2015 A simple spectrophotometric method has been described for the determination of procainamide hydrochloride. The method is based on the oxidation of procainamide hydrochloride by sodium periodate in the presence of sulfuric acid and measurement of the ...
S. Al-Tamrah, S. Al-Abbad
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Identification of novel DNA methylation inhibitors via a two-component reporter gene system [PDF]
Journal of Biomedical Science, 2011 Background Targeting abnormal DNA methylation represents a therapeutically relevant strategy for cancer treatment as demonstrated by the US Food and Drug Administration approval of the DNA methyltransferase inhibitors azacytidine and 5-aza-2 ...
Chen Ching-Shih +9 more
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Oral procainamide as pharmacological treatment of recurrent and refractory ventricular tachyarrhythmias: A single-center experience [PDF]
Heart Rhythm O2, 2021 Background: Antiarrhythmic therapy for recurrent ventricular arrhythmias in patients who have undergone catheter ablation, and in whom amiodarone and/or beta-blockers were ineffective or contraindicated, is a controversial issue.
Mauro Toniolo, MD +7 more
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Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. [PDF]
Journal of Clinical Investigation, 1993 Human antigen-specific CD4+ T cells become autoreactive after treatment with various DNA methylation inhibitors, including 5-azacytidine, procainamide, and hydralazine.
Jawaid Quddus +6 more
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Mechanisms of drug‐induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo [PDF]
Arthritis & Rheumatism, 1997 OBJECTIVE T cells treated with DNA methylation inhibitors overexpress lymphocyte function-associated antigen 1 (LFA-1), which results in autoreactivity, and the autoreactive cells cause a lupus-like disease in vivo, suggesting a mechanism by which some ...
Raymond Yung +4 more
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Emergency Department Use of Intravenous Procainamide for Patients with Acute Atrial Fibrillation or Flutter [PDF]
Academic Emergency Medicine, 2007 OBJECTIVES Acute atrial fibrillation and flutter are very common arrhythmias seen in emergency department (ED) patients, but there is no consensus for their optimal management.
Ian G. Stiell +5 more
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Journal of Pharmaceutical Analysis, 2017 Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug.
Kirthi Byadagi +3 more
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Adverse reactions to procainamide. [PDF]
British Journal of Clinical Pharmacology, 1977 1 Data from a comprehensive drug surveillance programme are analysed to provide details of procainamide use and toxicity in medical wards of teaching hospitals in five countries. 2 Out of a total of 488 recipients 9.2% had one or more adverse effect attributed to the drug; common effects being arrhythmias, gastro‐intestinal upsets and drug fever ...
Hershel Jick, D H Lawson
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THE GANGLION BLOCKING ACTION OF PROCAINAMIDE [PDF]
British Journal of Pharmacology and Chemotherapy, 1964 In cats and rabbits procainamide (20 to 50 mg, intravenously) produced a fall of blood pressure of 20 to 50 mm Hg which reached a maximal effect within 1 min and lasted for about 5 min. Procainamide reduced the pressor responses to nicotine and to carotid arterial occlusion and reduced the depressor response to vagal stimulation, but did not antagonize
J. W. Thompson, W. D. M. Paton
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