Results 41 to 50 of about 5,581 (154)

Myocardial toxicity in two dogs with natural exposure to ractopamine

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract Two dogs that lived in a farm setting were presented to the Texas A&M University Veterinary Medical Teaching Hospital's Emergency Service exhibiting muscle tremors and ventricular arrhythmias following ingestion of ractopamine, a ß‐2 agonist feed‐additive used in beef cattle, pigs and turkeys intended for slaughter to increase muscle mass. The
Sophie Tippit   +3 more
wiley   +1 more source

Brugada Syndrome or Phenocopy? Diagnostic Challenge in Patients with Pectus Excavatum

open access: yesJournal of Cardiac Arrhythmias, 2020
Brugada syndrome is an autosomal dominant heart disease caused by dysfunctions in the ionic channels, whose carriers present a classic electrocardiographic pattern and predisposition to malignant ventricular arrhythmias. The electrocardiogram alterations
Kárila Scarduelli Luciano   +3 more
doaj   +4 more sources

The Analysis of Human Serum N-Glycosylation in Patients with Primary and Metastatic Brain Tumors

open access: yesLife, 2021
The identification of patients with different brain tumors is solely built on imaging diagnostics, indicating the need for novel methods to facilitate disease recognition.
Csaba Váradi   +5 more
doaj   +1 more source

A retrospective study on laboratory‐confirmed acute Chinese medicine poisoning involving aconite in Hong Kong from 2008 to 2020

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
Abstract Background Territory‐wide epidemiological studies of acute Chinese medicine poisoning involving aconite after 2010 are lacking. Objectives To characterise the latest trends, presumed causes, clinical presentations, healthcare utilisation and patient outcomes of such poisoning cases in Hong Kong.
Rex Pui Kin Lam   +9 more
wiley   +1 more source

Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs. [PDF]

open access: yesPLoS ONE, 2013
DNA methylation is an epigenetic modification that regulates gene expression by DNA methyltransferases (DNMTs). Inhibition of DNMTs is a promising approach for cancer therapy.
Jakyung Yoo   +2 more
doaj   +1 more source

Contemporary Perspectives on J‐Wave Syndromes: An Expert Consensus Statement

open access: yesJournal of Arrhythmia, Volume 42, Issue 1, February 2026.
ABSTRACT J‐wave syndromes (JWS)—comprising Brugada syndrome (BrS) and early repolarization syndrome (ERS)—are important causes of malignant ventricular arrhythmias and sudden cardiac death in patients whose hearts appear structurally normal. Since the 2016 consensus, advances in genetics, pathophysiology, and therapy have redefined both understanding ...
Koonlawee Nademanee   +22 more
wiley   +1 more source

ECG Markers of Positive Drug Challenge With Ajmaline in Patients With Brugada Syndrome

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
A prominent S‐wave in lead II on a nondiagnostic baseline ECG is a powerful predictor for unmasking Brugada syndrome during an ajmaline challenge. This subtle sign enhances patient selection for provocation testing and aids in risk stratification, particularly in familial screening.
Erol Tülümen   +9 more
wiley   +1 more source

Myasthenia Gravis Outcomes After Use of Statins and Other Contraindicated Treatments: Results From the French National Insurance Database

open access: yesEuropean Journal of Neurology, Volume 33, Issue 1, January 2026.
In this real‐world study among 14,459 adults with MG, exposure to any contraindicated treatment was not significantly associated with risk of ICU admission for MG but was associated with significantly higher risk of death. In contrast, statins were associated with a greater risk of ICU admission but a lower risk of death.
Guilhem Solé   +7 more
wiley   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin   +16 more
wiley   +1 more source

Bundle Branch Reentrant Ventricular Tachycardia in a Patient with the Brugada Electrocardiographic Pattern

open access: yesAnnals of Noninvasive Electrocardiology, 2003
A 55‐year‐old, previously healthy man presented with an episode of wide QRS tachycardia that had left bundle branch morphology and left superior axis. His electrocardiogram in sinus rhythm showed characteristic Brugada pattern with coved type ST‐segment (
Alexander Mazur   +3 more
doaj   +1 more source

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