CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su +5 more
wiley +1 more source
The Semantic Units Framework, a technology-agnostic representational approach to FAIR and CLEAR knowledge infrastructures. [PDF]
Vogt L.
europepmc +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Patient autonomy and Patient Blood Management: lessons from the Pindo Mulla v. Spain Case. [PDF]
Perez-Ferrer A, Shander A, Muñoz M.
europepmc +1 more source
Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu +13 more
wiley +1 more source
The Bayesian audit: evaluating the proportionality of scientific claims to evidence - a case study on social priming and walking speed. [PDF]
Costa T.
europepmc +1 more source
Moving beyond projects: a logic model evaluation of an established translational simulation program. [PDF]
Petrosoniak A +7 more
europepmc +1 more source
From reaction to prevention: rethinking vocal fold paralysis after thyroid surgery. [PDF]
Aleman R +3 more
europepmc +1 more source
Adaptive Control of the Redundant Axis of a Surgical Robot for Operating Room Workspace Optimization Using Reinforcement Learning. [PDF]
Renedo-Alonso I +3 more
europepmc +1 more source

