Results 31 to 40 of about 1,092,525 (253)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

THE COMPOSITION OF PARTIES IN CLAIMS FOR UNJUST ENRICHMENT: STRUCTURE OF PARTICIPANTS AND PROCEDURAL CONSEQUENCES OF THEIR SUBSTITUTION [PDF]

Legal Bulletin
The article examines the composition of parties in claims for the recovery of unjust enrichment, identifies criteria for determining the proper defendant, and analyzes the procedural consequences of replacing an improper party during judicial proceedings.
SHASHLOV D.S.
doaj   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

THE ABSENCE OF A HASH SUM AS A PROCEDURAL ERROR ARISING IN A FORENSIC EXAMINATION WHEN ANALYSING OBJECTS IN A DIGITAL FORM

Правовое государство: теория и практика
An urgent task when working with digital objects is to comply with procedural rules and regulations in appointing a forensic examination and conducting research.
SHIKHALIYEVA Seldjan Zaur qizi
doaj   +1 more source

QUANTITATIVE METHODS AND RESEARCH IN SOCIAL SCIENCE: LOGIC AND UTILITY OF THE USE OF QUANTIFICATION IN THE EXPLANATIONS OF SOCIAL PHENOMENA

Mediações: Revista de Ciências Sociais, 2013
The article presents a theoretical analysis on methodological foundations (not only procedural) of so-called "quantitative methods" in social science research, which are often – but mistakenly – reduced to the idea of "quantification techniques".
Marília Patta Ramos
doaj   +1 more source

PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science

Advanced Engineering Materials, EarlyView.
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley   +1 more source

Dynamic Difficulty Adjustment Berbasis Logika Fuzzy Untuk Procedural Content Generation Pada Permainan Roguelike

Teknika, 2022
Perkembangan industri video game sangatlah pesat hingga ada banyak sekali orang yang memainkan video game. Setiap orang memiliki tingkat keterampilan yang berbeda dan memiliki kurva belajar yang unik untuk setiap video game yang mereka mainkan ...
David Saputra Octadianto Soedargo, Hartarto Junaedi   +1 more
doaj   +1 more source

Soft Mechanical‐Electrical Logic Using Liquid Metal‐Filled 3D‐Printed Architectures

Advanced Engineering Materials, EarlyView.
We present 3D‐printed soft mechanical–electrical logic elements that use liquid metal–filled silicone tubes actuated by thermoplastic polyurethane/polylactic acid (TPU/PLA) architectures to produce Boolean operations. Complementary normally open and normally closed unit cells perform repeatable binary transitions and can be combined into more complex ...
Christoph Lehmann, Ryan Kalgreen, Laura M. Comella   +2 more
wiley   +1 more source

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source

Compositional Semantics for the Procedural Interpretation of Logic [PDF]

International Conference on Logic Programming, 2006
Semantics of logic programs has been given by proof theory, model theory and by fixpoint of the immediate-consequence operator. If clausal logic is a programming language, then it should also have a compositional semantics.
M. H. Emden
semanticscholar   +1 more source