Results 91 to 100 of about 128,839 (232)

A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data

Advanced Engineering Materials, EarlyView.
Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour, Prithwish Tarafder, Anton Wiberg, Huanyu Li, Johan Moverare, Patrick Lambrix   +5 more
wiley   +1 more source

Impact of Sustainable Binders Based on Lignin and Collagen on the Volume Stability and Mechanical Properties of MgO‐C Refractories with MgO‐C Recyclates

Advanced Engineering Materials, EarlyView.
Collagen hydrolysate is evaluated as a sustainable binder for MgO‐C refractories. Its thermally induced cross‐linking and gas release lead to expansion and cracking in large bricks, but tailored batches with lignin, recyclates, or fine graphite improve the gas release while thermal treatment and stability.
Till M. J. Stadtmüller, Florian Kerber, Kirsten Moritz, Steffen Dudczig, Konstantin Kraushaar, Thomas Schemmel, Jana Hubálková, Patrick Gehre, Christos G. Aneziris   +8 more
wiley   +1 more source

A compact microflow liquid chromatography system for at-sample reaction monitoring of pharmaceutical active ingredient synthesis

Journal of Pharmaceutical and Biomedical Analysis Open
Process analytical technology (PAT) and real-time release testing (RTRT) are transforming pharmaceutical manufacturing by enabling continuous quality assurance through real-time process data rather than traditional end-product testing.
Shing Chung Lam, Penelope Huggins, Shanmugapriya Vasudevan, Boyjie Firme, Laell Raiteri, Andrew A. Gooley   +5 more
doaj   +1 more source

Analytical Quality by Design: A Tool for Regulatory Flexibility and Robust Analytics

International Journal of Analytical Chemistry, 2015
Very recently, Food and Drug Administration (FDA) has approved a few new drug applications (NDA) with regulatory flexibility for quality by design (QbD) based analytical approach.
Ramalingam Peraman, Kalva Bhadraya, Yiragamreddy Padmanabha Reddy   +2 more
doaj   +1 more source

Development of Sustainable MgO–C Refractories Using MgO–C Recyclates and a Novel Eco‐Friendly Fructose–Tannin Binder Crosslinked With Citric Acid

Advanced Engineering Materials, EarlyView.
This study develops sustainable MgO–C refractories using recycled materials and eco‐friendly fructose–tannin binders. The enhanced performance of citric acid as a cross‐linker and functional additives on mechanical and thermomechanical properties was examined. Characterization included strength tests, immersion trials, and microstructural and inclusion
Dinesh K. Gunasekar, Jana Hubálková, Steffen Dudczig, Gert Schmidt, Florian Kerber, Thomas Schemmel, Patrick Gehre, Christos G. Aneziris   +7 more
wiley   +1 more source

Additive manufacturing of prototype elements with process interfaces for continuously operating manufacturing lines

Asian Journal of Pharmaceutical Sciences, 2018
Rapid prototyping based on in silico design and 3D printing enables fast customization of complex geometries to multiple needs. This study utilizes, additive manufacturing for rapid prototyping of elements for continuously operating mixing geometries ...
Cosima Hirschberg, Mikkel Schmidt Larsen, Johan Peter Bøtker, Jukka Rantanen   +3 more
doaj   +1 more source

Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production

Engineering in Life Sciences, 2013
The process analytical technology (PAT) initiative is now 10 years old. This has resulted in the development of many tools and software packages dedicated to PAT application on pharmaceutical processes. However, most applications are restricted to small molecule drugs, mainly for the relatively simple process steps like drying or tableting where only a
Streefland, M., Martens, D.E., Beuvery, E.C., Wijffels, R.H.   +3 more
openaire   +2 more sources

Impact of Pre‐Oxidation Treatments on a Recycled MgO/Steel‐Composite as Carbon Free Anode in Aluminum‐Electrolysis Environments

Advanced Engineering Materials, EarlyView.
Cermets (60 vol.% AISI 316L stainless steel, 40 vol.% recycled MgO), intended for use in aluminum electrolysis, were pre‐oxidized in three furnaces with different heating technologies and subjected to a cryolite corrosion test. The different atmospheres influenced the formation of oxide layers, which in turn affected corrosion resistance and ...
Patricia Kaiser, Felix Drechsler, Nora Brachhold, Florian Kerber, Christos G. Aneziris   +4 more
wiley   +1 more source

Pharmaceutical Technology: Drug Delivery, Formulation, and Process Research

CHIMIA, 2006
This paper describes in the introduction the actual research trends in the area of pharmaceutical technology and the impact of FDA's PAT (Process Analytical Technology) Initiative on this research field.
Hans Leuenberger
doaj   +1 more source

Bioinspired Shape‐Memory Hook Fasteners With Programmable Interlocking and Silent Release

Advanced Engineering Materials, EarlyView.
Bioinspired hook fasteners made from epoxy shape‐memory polymers are shown to switch between strong, secure attachment and gentle, silent release when heated. By combining programmable geometry and material response, these adaptive fasteners outperform commercial systems in strength and noise control, enabling new solutions for robotics, medical ...
Maria I. Vallejo Ciro, Manuel J. Carvajal Loaiza, Rahaf Homssi, Vanessa Restrepo   +3 more
wiley   +1 more source