Results 71 to 80 of about 4,485 (254)

Clinical Validation of Artificial Intelligence (AI)‐based Cartilage Segmentation Predicting Knee Replacement

open access: yesArthritis Care &Research, Accepted Article.
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein   +3 more
wiley   +1 more source

Additive manufacturing of prototype elements with process interfaces for continuously operating manufacturing lines

open access: yesAsian Journal of Pharmaceutical Sciences, 2018
Rapid prototyping based on in silico design and 3D printing enables fast customization of complex geometries to multiple needs. This study utilizes, additive manufacturing for rapid prototyping of elements for continuously operating mixing geometries ...
Cosima Hirschberg   +3 more
doaj   +1 more source

Low‐Temperature Imidization of Polyimides (PI) for Scalable Manufacturing of Flexible Wearable Electronics

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐temperature imidization of PEG‐modified polyimide enables fully screen‐printed, roll‐to‐roll fabrication of flexible electrodes on PET substrates, delivering robust mechanical durability and reliable ECG/EMG signal performance for wearable electronics.
Akib Abdullah Khan, Jong‐Hoon Kim
wiley   +1 more source

A compact microflow liquid chromatography system for at-sample reaction monitoring of pharmaceutical active ingredient synthesis

open access: yesJournal of Pharmaceutical and Biomedical Analysis Open
Process analytical technology (PAT) and real-time release testing (RTRT) are transforming pharmaceutical manufacturing by enabling continuous quality assurance through real-time process data rather than traditional end-product testing.
Shing Chung Lam   +5 more
doaj   +1 more source

Pharmaceutical Technology: Drug Delivery, Formulation, and Process Research

open access: yesCHIMIA, 2006
This paper describes in the introduction the actual research trends in the area of pharmaceutical technology and the impact of FDA's PAT (Process Analytical Technology) Initiative on this research field.
Hans Leuenberger
doaj   +1 more source

A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour   +5 more
wiley   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

open access: yesAdvanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares   +3 more
wiley   +1 more source

An Application of X-Ray Fluorescence as Process Analytical Technology (PAT) to Monitor Particle Coating Processes

open access: yesChemical and Pharmaceutical Bulletin, 2018
An attempt to apply X-Ray Fluorescence (XRF) analysis to evaluate small particle coating process as a Process Analytical Technologies (PAT) was made. The XRF analysis was used to monitor coating level in small particle coating process with at-line manner. The small particle coating process usually consists of multiple coating processes.
Nakano, Yoshio   +2 more
openaire   +3 more sources

Experimental Characterization and Constitutive Modeling of the Effect of Prior Inelastic Strain on the Viscoplastic Behavior of AD730 at 700 °C

open access: yesAdvanced Engineering Materials, EarlyView.
This study shows that superalloys used in aircraft engine disks become much more prone to deformation at high temperatures if they have been strained during manufacturing. This effect increases with the level of prior strain but eventually reaches a limit.
Fabio Machado Alves da Fonseca   +9 more
wiley   +1 more source

Application of quality by design in the current drug development

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
Quality by Test was the only way to guarantee quality of drug products before FDA launched current Good Manufacturing Practice. To clearly understand the manufacture processes, FDA generalized Quality by Design (QbD) in the field of pharmacy, which is ...
Lan Zhang, Shirui Mao
doaj   +1 more source

Home - About - Disclaimer - Privacy