Understanding requirements engineering process: a challenge for practice and education [PDF]
, 2005 Reviews of the state of the professional practice in Requirements Engineering (RE) stress that the RE process is both complex and hard to describe, and suggest there is a significant difference between competent and "approved" practice.
Armarego, J., Nguyen, L., Swatman, P.
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A Product Line Systems Engineering Process for Variability Identification and Reduction
, 2018 Software Product Line Engineering has attracted attention in the last two decades due to its promising capabilities to reduce costs and time to market through reuse of requirements and components.
Dickerson, Charles +4 more
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A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Modelling and managing reliability growth during the engineering design process [PDF]
, 2010 [This is a keynote speech presented at the 2nd International Conference on Design Engineering and Science, discussing modelling and managing reliability growth during the engineering process.] Reliability is vital for safe and efficient operation of ...
Quigley, J.L., Walls, Lesley
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A Boxology of Design Patterns for Hybrid Learning and Reasoning Systems [PDF]
, 2019 We propose a set of compositional design patterns to describe a large variety of systems that combine statistical techniques from machine learning with symbolic techniques from knowledge representation.
Teije, Annette ten, van Harmelen, Frank
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FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Generative artificial intelligence in chemical engineering spans multiple scales
Frontiers in Chemical EngineeringRecent advances in generative artificial intelligence (GenAI), particularly large language models (LLMs), are profoundly impacting many fields. In chemical engineering, GenAI plays a pivotal role in the design, scale-up, and optimization of chemical and ...
Benjamin Decardi-Nelson +6 more
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Innentitelbild: Strain Engineering of a MXene/CNT Hierarchical Porous Hollow Microsphere Electrocatalyst for a High‐Efficiency Lithium Polysulfide Conversion Process (Angew. Chem. 5/2021) [PDF]
, 2021 Xin Wang +13 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
CT&F Ciencia, Tecnología & Futuro, 1998 This article presents the current status of the use of Artificial Neural Networks (ANNs) in process engineering applications where common mathematical methods do not completely represent the behavior shown by experimental observations, results, and plant
F OTERO
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