Results 71 to 80 of about 23,342,644 (373)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Generative artificial intelligence in chemical engineering spans multiple scales

open access: yesFrontiers in Chemical Engineering
Recent advances in generative artificial intelligence (GenAI), particularly large language models (LLMs), are profoundly impacting many fields. In chemical engineering, GenAI plays a pivotal role in the design, scale-up, and optimization of chemical and ...
Benjamin Decardi-Nelson   +6 more
doaj   +1 more source

Two-dimensional molybdenum carbide 2D-Mo2C as a superior catalyst for CO2 hydrogenation

open access: yesNature Communications, 2021
The development of robust and efficient catalysts for CO2 hydrogenation to value-added chemicals is an urgent task. Here the authors report two-dimensional carbide catalyst based on earth-abundant molybdenum that hydrogenates CO2 with high activity ...
Hui Zhou   +7 more
doaj   +1 more source

Engineering design process

open access: yesDesign Methodology in Rock Engineering, 2020
The aim of the article is to present an experiment carried out by some female students and the results of a study that was conducted to identify and describe some of the relationships between access to STEM education, which includes focusing on ...
Dr. S. P. Tayal
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

The improvement of maintenance service for traction networks equipment on the base of process approach

open access: yesNauka ta progres transportu, 2014
Purpose. The new methods development for improving the maintenance service for equipment of traction networks in order to increase its efficiency and quality. Methodology.
D. V. Mironov
doaj   +1 more source

Influence of Several Phosphate-Containing Additives on the Stability and Electrochemical Behavior of Positive Electrolytes for Vanadium Redox Flow Battery

open access: yesEnergies, 2022
The poor operational stability of electrolytes is a persistent impediment in building redox flow battery technology; choosing suitable stability additives is usually the research direction to solve this problem.
Xukun Zhang   +5 more
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli

open access: yesMicrobial Cell Factories, 2023
Background Palifermin (trade name Kepivance®) is an amino-terminally truncated recombinant human keratinocyte growth factor 1 (KGF-1) with 140 residues that has been produced using Escherichia coli to prevent and treat oral mucositis following radiation ...
Young Su Kim   +7 more
doaj   +1 more source

Guidance for requirements engineering processes [PDF]

open access: yes, 1997
Guidance plays a crucial role in requirements engineering as this task is both ill defined and highly intellectual. Guidance can be provided once the goal to be achieved has been identified. Two kinds of guidance are proposed, point and flow guidance. The former supports the fulfillment of goals whereas the latter helps in goal identification. Guidance
Si-Said, Samira, Rolland, Colette
openaire   +3 more sources

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