Results 71 to 80 of about 5,105,474 (332)
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Understanding requirements engineering process: a challenge for practice and education [PDF]
, 2005 Reviews of the state of the professional practice in Requirements Engineering (RE) stress that the RE process is both complex and hard to describe, and suggest there is a significant difference between competent and "approved" practice.
Armarego, J., Nguyen, L., Swatman, P.
core +1 more source
Using protocol analysis to explore the creative requirements engineering process
, 2006 Protocol analysis is an empirical method applied by researchers in cognitive psychology and behavioural analysis. Protocol analysis can be used to collect, document and analyse thought processes by an individual problem solver.
Nguyen, Lemai, Shanks, Graeme
core +2 more sources
A Boxology of Design Patterns for Hybrid Learning and Reasoning Systems [PDF]
, 2019 We propose a set of compositional design patterns to describe a large variety of systems that combine statistical techniques from machine learning with symbolic techniques from knowledge representation.
Teije, Annette ten, van Harmelen, Frank
core +2 more sources
CT&F Ciencia, Tecnología & Futuro, 1998 This article presents the current status of the use of Artificial Neural Networks (ANNs) in process engineering applications where common mathematical methods do not completely represent the behavior shown by experimental observations, results, and plant
F OTERO
doaj
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Modelling and managing reliability growth during the engineering design process [PDF]
, 2010 [This is a keynote speech presented at the 2nd International Conference on Design Engineering and Science, discussing modelling and managing reliability growth during the engineering process.] Reliability is vital for safe and efficient operation of ...
Quigley, J.L., Walls, Lesley
core
Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
eXplainable Artificial Intelligence in Process Engineering: Promises, Facts, and Current Limitations
Applied System InnovationArtificial Intelligence (AI) has been swiftly incorporated into the industry to become a part of both customer services and manufacturing operations.
Luigi Piero Di Bonito +4 more
doaj +1 more source