Results 51 to 60 of about 1,229,325 (306)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Digitalization of educational organizations as a product- and process-innovation in the data economy: managerial and methodological aspects

open access: yesRussian Journal of Economics and Law
Objective: to reveal the essence of educational organizations’ digitalization as the implementation of product- and processinnovations in their innovation activity from the managerial viewpoint, including (here) innovation statistics in the data economy.
A. I. Shinkevich   +2 more
doaj   +1 more source

Features and critical issues of process innovations

open access: yesAgathón, 2019
‘Process’ innovations – inclusive (but not substitutive) of similar ‘product’ evolutions (and further factors with which unravel activities of architecture’s production and management) – represent as many ‘countermeasures’ to the challenges posed by the ...
Giorgio Giallocosta
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

On Competition and the Strategic Management of Intellectual Property in Oligopoly [PDF]

open access: yes, 2009
An innovative firm with private information about its indivisible process innovation chooses strategically whether to apply for a patent with probabilistic validity or rely on secrecy.
Jansen, Jos
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

ANALYSIS OF TECHNOLOGICAL INNOVATIONS MANAGEMENT AT RUSSIAN INDUSTRIAL ENTERPRISES: SOURCES OF FINANCING, INNOVATIVE STRATEGY

open access: yesRussian Journal of Economics and Law, 2012
The article analyzes technological innovations management at Russian industrial enterprises, basing on the study of financial sources of the innovative-technological activity of industrial enterprises, determining the type of innovative strategy of ...
G. I. Gumerova, E. S. Shaymieva
doaj   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Environmental innovations and sustainability practices of manufacturing firms in Uganda [PDF]

open access: yesAsia Pacific Journal of Innovation and Entrepreneurship
Purpose – The purpose of this study is to investigate the pivotal role of environmental innovations in driving sustainability practices within medium and large manufacturing firms operating in Uganda. Design/methodology/approach – Using a cross-sectional
Kassim Alinda   +2 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy