Results 141 to 150 of about 25,592,602 (307)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Investigation of the effect of different process variables on color and physical properties of viscose and cotton knitted fabrics. [PDF]

Heliyon, 2021
Hossain I, Moniruzzaman M, Maniruzzaman M, Jalil MA.   +3 more
europepmc   +1 more source

Systematic Review of SMART Recovery: Outcomes, Process Variables, and Implications for Research

Psychology of Addictive Behaviors, 2017
A. Beck, Erin Forbes, A. Baker, P. Kelly, F. Deane, A. Shakeshaft, David Hunt, J. Kelly   +7 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

DOE-based synthesis of gellan gum-acrylic acid-based biodegradable hydrogels: screening of significant process variables and in situ field studies. [PDF]

RSC Adv, 2022
Choudhary S, Sharma K, Bhatti MS, Sharma V, Kumar V.   +4 more
europepmc   +1 more source

Quality by Design approach for studying the impact of formulation and process variables on product quality of oral disintegrating films.

International journal of pharmaceutics, 2017
Sonal Mazumder, Naresh Pavurala, P. Manda, Xiaoming Xu, Celia N. Cruz, Y. Krishnaiah   +5 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of Process Variables on Rice Flour Functional Properties, and Porous Structure of Rice and Wheat-Based Leavened Food Products. [PDF]

Food Technol Biotechnol, 2022
Rathnayake HA, Navaratne S, Navaratne C.
europepmc   +1 more source

Client Perceptions of Helpfulness in Therapy: a Novel Video-Rating Methodology for Examining Process Variables at Brief Intervals During a Single Session

Behavioural and Cognitive Psychotherapy, 2017
Alexandra A. Cocklin, W. Mansell, R. Emsley, P. McEvoy, Chloe Preston, J. Comiskey, S. Tai   +6 more
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source