Results 91 to 100 of about 31,552 (309)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Development of a new PM titanium alloy for improved processability
The application of titanium and its alloys are fast expanding from large sized aerospace components to small components such as hand phone covers. They are restricted by the processability and the economics of use of titanium despite the advantages that ...
Yarlagadda, Prasad K. +4 more
core +1 more source
Exploration of increased electrode surface area through laser structuring is undertaken to improve performance. While nanosecond lasers offer cost-effective processing, femtosecond lasers achieve a minimal heat effect, excelling in precision.
Jaegeun Shin, Juhee Yang, Dongkyoung Lee
doaj +1 more source
4-nonylphenoxy-1, 2-dinitrilbenzene (NP-ph), a novel kind of phthalonitrile containing flexible hydrocarbyl chains, has been synthesized. The structures of NP-ph were investigated by Nuclear Magnetic Resonance Spectroscopy (1H-NMR) and Fourier Transform ...
M. Z. Xu +4 more
doaj +1 more source
A Process Warehouse for Process Variants Analysis
Process model variants are collections of similar process models evolved over time because of the adjustments that were made to a particular process in a given domain, e. g.,order-to-cash or procure-to-pay process in reseller or procurement domain. These adjustments produce some variations between these process models that mainly should be identical ...
openaire +5 more sources
An overview is given of the processing of plastic materials from the handling of polymers in the pellet and powder form to manufacturing of a plastic fabricated product. Various types of equipment used and melt processing ranges of various polymer formulations to make the myriad of plastic products that are commercially available are discussed.
openaire +3 more sources
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
This paper exhibits accurate encodings of the λ-calculus in the π-calculus. The former is canonical for calculation with functions, while the latter is a recent step (Milner et al. 1989) towards a canonical treatment of concurrent processes. With quite simple encodings, two λ-calculus reduction strategies are simulated very closely; each reduction in λ-
openaire +3 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

