Results 71 to 80 of about 31,552 (309)
Noncolliding processes, matrix-valued processes and determinantal processes
v2:AMS-LaTeX, 32 pages, 3 figures, 3 tables, minor correction made, to be published in Sugaku Expositions (AMS)
Katori, Makoto, Tanemura, Hideki
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Language typology and processability theory
The focus of this chapter is on the typological plausability of Processability Theory (PT, Pienemann 1998). The chapter investigates how languages across typology encode grammatical relations (SUBJ and OBJ, etc) using different means of syntactic or ...
Kawaguchi, Satomi, Kessler, Jörg-U.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Deterministic receptive processes are kahn processes
Deterministic asynchronous concurrent formalisms are valuable because determinism greatly simplifies the design and validation of such systems and most concurrent formalisms are nondeterministic. This paper connects two of the more successful deterministic asynchronous formalisms: Kahn's dataflow networks and Josephs's deterministic receptive processes.
Edwards, Stephen A., Tardieu, Olivier
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Extending processability theory
The original version of PT focused on modelling the transfer of grammatical information within c(onstituent) structure on the basis of feature unification, utilising a simplified version of f( unctional) structure. In this chapter we will explore ways in
Kawaguchi, Satomi +2 more
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Delays and deficits in structural language and social communication are common features of autism spectrum disorder (ASD), but the exact nature of these problems is unclear.
Best, Catherine T. (R11322) +1 more
core

