Results 61 to 70 of about 31,552 (309)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Visualizing the Process of Process Modeling with PPMCharts [PDF]

open access: yes, 2013
In the quest for knowledge about how to make good process models, recent research focus is shifting from studying the quality of process models to studying the process of process modeling (often abbreviated as PPM) itself. This paper reports on our efforts to visualize this specific process in such a way that relevant characteristics of the modeling ...
Jan Claes   +5 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Book review: Understanding second language processing: focus on processability theory [PDF]

open access: yes, 2019
Review of Dyson, BP, Hakansson, G (2017) 'Book review: Understanding second language processing: focus on processability theory' John Benjamins ...
Chan, Sathena
core   +1 more source

Evaluating the Global Processability of Anthropogenic Metals from Mining Waste

open access: yesResources
Natural resource depletion and increased mining waste pose significant challenges to global sustainability efforts. This study investigates the processability of mining waste during the metal recovery stage to evaluate its potential contribution to ...
Qudsia Kanwal   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The influence of processing additives on the processability and properties of styrene-butadiene rubber

open access: yesТонкие химические технологии, 2011
Short review devoted to prediction of phase morphologies of heterogeneous polymer blends with the aim of the development of novel composite polymeric materials.
D. V. Sitnikova, A. M. Bukanov
doaj  

Thiol-Functionalized Covalent Organic Framework for Efficient Metal Ion Removal in Water Treatment

open access: yesNanomaterials
Advanced water treatment technologies must offer selective, efficient, and cost-effective contaminant removal. In this study, TPB-DMTP-COF-SH, prepared from 1,3,5-tris(4-aminophenyl)benzene (TPB) and 2,5-dimethoxyterephaldehyde (DMTP), was synthesized ...
Cristina Arqueros   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Widening contexts for processability theory: theories and issues Processability approaches to language acquisition research & teaching ;, vol. 7./ edited by Anne Lenzing, Howard Nicholas, Jana Roos.

open access: yes, 2019
Includes bibliographical references and index."This book explores relationships between Processability Theory approaches and other approaches to SLA. It is distinctive in two ways.
Lenzing Anke, Roos Jana, Nicholas Howard
core  

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