Results 81 to 90 of about 172,960 (308)

Geomorphological Characterization of the Colombian Orinoquia

open access: yesLand
The Colombian Orinoquia was shaped within a tectonic and sedimentary framework linked to the uplift of the Andean cordilleras during the Oligocene–Miocene.
Larry Niño   +5 more
doaj   +1 more source

An Improved Approach for Downscaling Coarse-Resolution Thermal Data by Minimizing the Spatial Averaging Biases in Random Forest

open access: yesRemote Sensing, 2020
Land surface temperature (LST) plays a fundamental role in various geophysical processes at varying spatial and temporal scales. Satellite-based observations of LST provide a viable option for monitoring the spatial-temporal evolution of these processes.
Sammy M. Njuki   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A simple stochastic model describing the evolution of genomic GC content in asexually reproducing organisms

open access: yesScientific Reports, 2022
A genome’s nucleotide composition can usually be summarized with (G)uanine + (C)ytosine (GC) or (A)denine + (T)hymine (AT) frequencies as GC% = 100% − AT%.
Jon Bohlin
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Large deviation results for branching processes in fixed and random environments [PDF]

open access: yes, 1994
This thesis considers three different aspects of large deviations for branching processes. First, we study the deviation between the empirical mean and the true mean. Second, we investigate the large deviation behavior exhibited by the tail of the random
Vidyashankar, Anand
core   +1 more source

Physical, Chemical and Biological Effects on Soil Bacterial Dynamics in Microscale Models

open access: yesFrontiers in Ecology and Evolution, 2020
Soil is populated by highly diverse microbial communities mediating important processes and functions. The distribution of microbes, however, is neither uniform nor random.
Sara König   +4 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Random walks on Galton-Watson trees with infinite variance offspring distribution conditioned to survive [PDF]

open access: yes, 2008
We establish a variety of properties of the discrete time simple random walk on a Galton-Watson tree conditioned to survive when the offspring distribution, Z say, is in the domain of attraction of a stable law with index alpha is an element of (1,2]. In
Croydon, David A., Kumagai, Takashi
core  

Maximum entropy modelling of sub-optimal transport

open access: yesCommunications Physics
Many natural systems involve structures shaped by competing forces: efficiency, randomness, and incomplete information. To the best of our knowledge, there is currently no robust method to assess the presence of optimization processes in real networks ...
Lorenzo Buffa   +5 more
doaj   +1 more source

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