Results 81 to 90 of about 84,402,451 (356)

Examining the link between information processing speed and executive functioning in multiple sclerosis

open access: yes, 2009
Slowed information processing speed (IPS) is frequently reported in those with multiple sclerosis (MS), and at least 20% are compromised on some aspect of executive functioning also.
Drew, Margaret A.   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

RecNMP: Accelerating Personalized Recommendation with Near-Memory Processing [PDF]

open access: yesInternational Symposium on Computer Architecture, 2019
Personalized recommendation systems leverage deep learning models and account for the majority of data center AI cycles. Their performance is dominated by memory-bound sparse embedding operations with unique irregular memory access patterns that pose a ...
Liu Ke   +20 more
semanticscholar   +1 more source

High working memory load leads to more Ebbinghaus illusion [PDF]

open access: yes, 2009
The evidence that distractor processing increases with greater load on working memory has come mainly from Stroop-type interference tasks, making it difficult to establish whether cognitive load affects distractor processing at the perceptual level or ...
De Fockert, J. W., Wu, Si
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Mammoth : gearing Hadoop towards memory-intensive MapReduce applications [PDF]

open access: yes, 2015
The MapReduce platform has been widely used for large-scale data processing and analysis recently. It works well if the hardware of a cluster is well configured.
Hai Jin   +15 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Effect of the recall time of autobiographical memory on conscious memory processing and automatic memory processing

open access: yesJournal of Human Environmental Studies, 2016
In this study, I investigated the effect of the recall time of autobiographical memory on conscious and automatic memory processes. Two-second and six-second recall time conditions were used as experimental variables in two different experiments.
Takashi Horiuchi
doaj   +1 more source

Working memory and its role in children’s scholastic attainment [PDF]

open access: yes, 2005
Previous research has identified links between working memory and scholastic skills. This thesis reports five studies that investigated both the role of working memory in children's scholastic attainment and the resources that underlie working memory ...
St Clair-Thompson, Helen
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy