Results 61 to 70 of about 149,979,910 (297)

A Digital Twin Approach for Spacecraft On-Board Software Development and Testing

open access: yesAerospace
The increasing complexity of spacecraft On-Board Software (OBSW) necessitates advanced development and testing methodologies to ensure reliability and robustness.
Andrea Colagrossi   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Loop B is a major structural component of the 5-HT3 receptor [PDF]

open access: yes, 2008
The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F).
Thompson, Andrew J.   +9 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Controle de Velocidade de uma Máquina de Ímãs Permanentes Tolerante a Falhas em Conjunto com Técnica de Máximo Torque por Ampere

open access: yesEletrônica de Potência
Com o grande avanço da utilização de veículos elétricos no mundo, devido ao alto nível de concorrência e com a busca da diminuição dos impactos ambientais que os veículos à combustíveis fósseis trazem, existe um crescimento na tentativa de aumentar a ...
João Batista Viana Neto   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Reinforced Model Predictive Guidance and Control for Spacecraft Proximity Operations

open access: yesAerospace
An increased level of autonomy is attractive above all in the framework of proximity operations, and researchers are focusing more and more on artificial intelligence techniques to improve spacecraft’s capabilities in these scenarios.
Lorenzo Capra   +2 more
doaj   +1 more source

Artificial Intelligence Integrated Fractional Order Control of Doubly Fed Induction Generator-Based Wind Energy System

open access: yesIEEE Access, 2021
This paper proposes an artificial intelligence integrated (AI) fractional order robust control for a DFIG based wind energy conversion system. To reduce the chattering phenomena in the excitation signal, fuzzy system is employed for the adaptive ...
Nasim Ullah   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Processor-in-the-Loop Simulations Applied to the Design and Evaluation of a Satellite Attitude Control [PDF]

open access: yes, 2014
The design of a controller requires a mathematic modeling followed by the adjusting of some model parameters. However to overcome the controller to a single piece of hardware, involves the codification of this mathematical based model into an appropriate firmware description suited to work correctly in a specific platform.
Luiz S.   +3 more
openaire   +1 more source

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