Results 81 to 90 of about 149,979,910 (297)

Toward Emotion-Aware Computing: A Loop Selection Approach Based on Machine Learning for Speculative Multithreading

open access: yesIEEE Access, 2017
Emotion-aware computing can recognize, interpret, process, and simulate human affects. These programs in this area are compute-intensive applications, so they need to be executed in parallel.
Bin Liu   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Agrégation seminar 2024

open access: yes
After our 2022 seminar with Marc Porée, and our 2023 seminar with Jeremy Elprin on Keats, Loop is proud to present the 2024 agrégation seminar: Claire Vial and Agnès Blandeau: On Sir Gawain and the Green Knight (text and film) Amélie Ducroux : On T.S ...
The LOOP team
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A Generic Actuator Management Solution for Space Applications Based on Convex Optimization

open access: yesAerospace
This paper addresses a common challenge in space systems: how to effectively manage multiple actuators under demanding mission conditions. We introduce a flexible, optimization-based algorithm designed to dispatch control commands among a set of ...
Jesús Ramírez   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Real-Time Processor-in-Loop Investigation of a Modified Non-Linear State Observer Using Sliding Modes for Speed Sensorless Induction Motor Drive in Electric Vehicles

open access: yesEnergies, 2020
Tracking performance and stability play a major role in observer design for speed estimation purpose in motor drives used in vehicles. It is all the more prevalent at lower speed ranges.
Mohan Krishna Srinivasan   +7 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Loop-invariant Code Motion Algorithm Based on Loop Cost Analysis [PDF]

open access: yesJisuanji kexue
Loop-invariant code motion(LICM) is a commonly used compilation optimization algorithm for loop structures in programs.By moving the invariant calculations in the loop body to outside the loop,the algorithm reduces the overhead of duplicate calculations ...
JIANG Jun, ZHAI Yanhe, ZENG Zhiheng, GU Yichao, HUANG Liangming
doaj   +1 more source

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