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Structural Cerebral Network Differences in Prodromal Alzheimer’s Disease and Prodromal Dementia with Lewy Bodies

Dementia and Geriatric Cognitive Disorders, 2022
Introduction: Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) have long prodromal phases without dementia. However, the patterns of cerebral network alteration in this early stage of the disease remain to be clarified. Method: Participants were 48 patients with mild cognitive impairment (MCI) due to AD (MCI-AD), 18 patients with MCI with ...
Miho Ota   +8 more
openaire   +2 more sources

Elevated Plasma Orexin-A Levels in Prodromal Dementia with Lewy Bodies

Journal of Alzheimer's Disease, 2022
Background: Studies on plasma orexin-A levels in prodromal dementia with Lewy bodies (DLB) and the relationship with clinical manifestations are rare. Objective: To assess plasma orexin-A levels and evaluate the correlation with clinical features in patients with mild cognitive impairment with Lewy bodies (MCI-LB) and DLB.
Jinghuan, Gan   +10 more
openaire   +2 more sources

Prodromal dementia with Lewy bodies

Geriatrics & Gerontology International, 2015
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementing disorder after Alzheimer's disease (AD), but there is limited information regarding the prodromal DLB state compared with that of AD. Parkinson's disease (PD) and DLB share common prodromal symptoms with Lewy body disease (LBD), allowing us to use a common strategy ...
Hiroshige, Fujishiro   +3 more
openaire   +2 more sources

Biomarkers and diagnosis of dementia with Lewy bodies including prodromal: Practical aspects

Revue Neurologique, 2022
Dementia with Lewy Bodies (DLB) is a common form of cognitive neurodegenerative disease. More than half of the patients affected are not or misdiagnosed because of the clinical similarity with Alzheimer's disease (AD), Parkinson's disease but also psychiatric diseases such as depression or psychosis.
F. Blanc, O. Bousiges
openaire   +2 more sources

Cognitive profile in prodromal disease (dementia) with Lewy bodies

Gériatrie et Psychologie Neuropsychiatrie du Viellissement, 2017
This paper reviews findings on cognition in prodromal dementia with Lewy bodies (DLB). The issue of differential diagnosis between DLB and Alzheimer's disease (AD) on the one hand, and Parkinson's disease (PD) on the other hand, at prodromal stages of the diseases is discussed.
Jennifer, Kemp   +4 more
openaire   +2 more sources

Testing Hippocampal Memory in Prodromal Dementia with Lewy Bodies

Journal of Alzheimer's Disease, 2018
The Free and Cued Selective Reminding test (FCSRT) was used to assess memory in 19 patients with prodromal dementia with Lewy bodies (DLB) and 25 Alzheimer’s disease (AD) patients. DLB scored better than AD in selective measures of the FCSRT: immediate total recall (p = 0.01) and index of sensitivity of cueing (p = 0.001), while free delayed and total ...
Bussè C   +10 more
openaire   +3 more sources

Diagnostic and prognostic value of EEG in prodromal dementia with Lewy bodies

Neurology, 2020
Early biomarkers for dementia with Lewy bodies (DLB) are lacking. To determine whether EEG differentiates the prodromal phase of DLB from other causes of mild cognitive impairment (MCI) and whether EEG is predictive for time to conversion from MCI to DLB, we compared EEGs and clinical follow-up of patients with MCI due to DLB with those of patients ...
Jessica Joanne van der Zande   +6 more
openaire   +3 more sources

Prodromal Dementia With Lewy Bodies Manifesting as Sertraline-induced Parkinsonism

Alzheimer Disease & Associated Disorders, 2012
To describe a patient with prodromal dementia with Lewy bodies (DLB) manifesting as sertraline-induced parkinsonism.Case report.Tertiary referral center.A 75-year-old man who initially presented with anxiety and depression along with mild cognitive impairment, later developed drug-induced parkinsonism because of sertraline treatment, and eventually ...
Jin-Hyuck, Kim   +6 more
openaire   +2 more sources

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