Results 121 to 130 of about 20,922 (255)

Exploiting Methyl Triazenes as Attractive Alternatives to Temozolomide and Dacarbazine for Cancer Therapy. [PDF]

Molecules
Ribeiro Morais G, Nwokolo GC, Lamptey Mills HNL, Wheelhouse RT, Falconer RA.   +4 more
europepmc   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Nanobody-Conjugated Theranostic Prodrug Targeting α_vβ₃ Integrin Enables Precision Cancer Therapy With Real-Time Imaging. [PDF]

Adv Healthc Mater
Karan S, Lee H, Naskar R, Cho MY, Park HS, Han EH, Hore S, Cho SH, Lam TNK, Son T, Park TJ, Hwang I, Sessler JL, Hong KS.   +13 more
europepmc   +1 more source

Exploiting vitamin C as a prooxidant to activate ROS-responsive prodrugs for potent and selective tumor killing. [PDF]

Redox Biol
Ali T, Ponnamperumage TNF, Miller CJ, Li D, Awoyera WO, Peterson AK, Gao H, Pandey J, Jakusz JAR, Fan H, Koelsch GE, Arnold LA, Jorns JM, Cheng YC, Roy A, Zhou G, Peng X.   +16 more
europepmc   +1 more source

Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives

iRADIOLOGY, EarlyView.
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo, Yuling Cui, Zhiye Fan, Chenxin Jiang, Bowen Fu, Guangbin Cui, Yanli He   +6 more
wiley   +1 more source

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine. [PDF]

Drug Test Anal
Wellenberg SK, Wagmann L, Kroesen MD, Schippers P, Grill M, Herrmann J, Meyer MR.   +6 more
europepmc   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

Radiotherapy meets anticancer metallodrugs. [PDF]

Med Rev (2021)
Zhang S, Shen S, Li J, Fu Q, Guo Z, Liu Z.   +5 more
europepmc   +1 more source

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou, John T. Leman, Harper Serringer, Ke Xia, Christopher N. LaFratta, Chaitanya Ullal, Edmund F. Palermo   +6 more
wiley   +1 more source

Enzymatic Laccase Nanoreactors Induce Apoptosis in MOLT-4-ALL Cells and Activate Prodrugs in a Synergetic Effect. [PDF]

Blood Lymphat Cancer
Medrano-Villagómez CA, Loredo-García E, Gasperin-Bulbarela J, Vazquez-Duhalt R.   +3 more
europepmc   +1 more source