Results 81 to 90 of about 4,767,137 (292)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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ComplexityThis study, employing convenience sampling of art specialists, investigates the emotional resonance of young consumers with Chinese bamboo patterns, underscoring their significance in the realm of contemporary design.
Muxing Gao, Xiaoxiao Cao, Lihuai Qian
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Scientific ReportsIn traditional Chinese living environments, architecture and furniture have long complemented each other, forming a unified spatial aesthetic. However, in contemporary China, a disconnect has emerged between furniture design and architectural styles in ...
Chao Li, S. Siti Suhaily, Yue Zhou
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IEEE Access, 2019 We present a design and the optimization of an irregular-shaped inward-outward (IO) ring-pair magnet array that generates a 1D monotonic field pattern for 2D head imaging in a low-field portable magnetic resonance imaging (MRI) system.
Zhi Hua Ren, Jia Gong, Shao Ying Huang
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Towards a change process planning tool [PDF]
, 2003 The relationship between a product and its design process is generally complex and not fully understood. When modifying a product, industry still rarely considers the implementation process and its consequences for other design activities in the company,
Clarkson, P. J., Eckert, C. M., Eger, T.
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Applied SciencesGenerative AI (Gen-AI) revolutionizes design by leveraging machine learning to generate innovative solutions. It analyzes data to identify patterns, creates tailored designs, enhances creativity, and allows designers to explore complex possibilities for ...
Prithvi Krishna Chittoor +5 more
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Trends and Design Relating literature to industry practice [PDF]
, 2008 In a crowded market place, where technology and functionality are not enough to differentiate a product from its competitors, the product’s appearance is a major driver of consumer preference.
Eckert, Claudia +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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