Results 1 to 10 of about 6,311,865 (181)

Prognostic model to identify and quantify risk factors for mortality among hospitalised patients with COVID-19 in the USA

open access: yesBMJ Open, 2021
Objectives To develop a prognostic model to identify and quantify risk factors for mortality among patients admitted to the hospital with COVID-19.Design Retrospective cohort study.
Shemra Rizzo   +7 more
doaj   +1 more source

Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays

open access: yesExploration of Neuroscience, 2023
Aim: Apolipoprotein E (ApoE) isoforms, especially the ApoE4 isoform, are genetic risk factors for Alzheimer’s disease (AD). Moreover, the APOE ε4 haplotype has a dose-dependent association with an increased risk of amyloid-related imaging abnormalities ...
Tatsushi Yuri   +8 more
doaj   +1 more source

Biodistribution of the saponin-based adjuvant Matrix-M™ following intramuscular injection in mice

open access: yesFrontiers in Drug Delivery, 2023
Novel adjuvants are extensively utilized in the development of safe and effective vaccines against emerging pathogens. Matrix-M™ adjuvant is a saponin-based adjuvant used in several active clinical development programs and in widespread use in the COVID ...
Cecilia Carnrot   +11 more
doaj   +1 more source

Productivity Developments Abroad [PDF]

open access: yesFederal Reserve Bulletin, 2000
This article reviews recent productivity trends in foreign industrial countries. The focus of the analysis is on whether productivity abroad has accelerated to an extent comparable to that observed in the United States. The authors find that foreign labor productivity, unlike that of the United States, has not accelerated in the latter half of the ...
Christopher J. Gust, Jaime R. Marquez
openaire   +1 more source

Evaluation of water quality index and geochemical characteristics of surfacewater from Tawang India

open access: yesScientific Reports, 2022
In this study,the water samples were collected from 31 sites of Tawang, Arunachal Pradesh, India (North-Eastern Himalaya), during the winter season to check the suitability of water for drinking and irrigation purposes.The study scientifically ...
Nisha Gaur   +5 more
doaj   +1 more source

Pick and place process for uniform shrinking of 3D printed micro- and nano-architected materials

open access: yesNature Communications, 2023
Two-photon polymerization lithography is promising for producing three-dimensional structures with user-defined micro- and nanoscale features. Additionally, shrinkage by thermolysis can readily shorten the lattice constant of three-dimensional photonic ...
Tomohiro Mori   +11 more
doaj   +1 more source

High throughput screening data for a case study of CHO cell culture process development

open access: yesData in Brief, 2021
In this article, we present four sets of data from high-throughput screening (HTS) studies of different chemically defined media using an industrially relevant Chinese hamster ovary (CHO) cell line.
Qin He   +9 more
doaj   +1 more source

Development of an intensified fed-batch production platform with doubled titers using N-1 perfusion seed for cell culture manufacturing

open access: yesBioresources and Bioprocessing, 2020
The goal of cell culture process intensification is to increase volumetric productivity, generally by increasing viable cell density (VCD), cell specific productivity or production bioreactor utilization in manufacturing.
Jianlin Xu   +7 more
doaj   +1 more source

N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing

open access: yesBioengineering, 2022
Fed-batch process intensification with a significantly shorter culture duration or higher titer for monoclonal antibody (mAb) production by Chinese hamster ovary (CHO) cells can be achieved by implementing perfusion operation at the N-1 stage for ...
Emily S. C. Rittershaus   +8 more
doaj   +1 more source

Upstream cell culture process characterization and in-process control strategy development at pandemic speed

open access: yesmAbs, 2022
As of early 2022, the coronavirus disease 2019 (COVID-19) pandemic remains a substantial global health concern. Different treatments for COVID-19, such as anti-COVID-19 neutralizing monoclonal antibodies (mAbs), have been developed under tight timelines.
Jianlin Xu   +4 more
doaj   +1 more source

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