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Product Development vs. Production Development
Procedia CIRP, 2014 AbstractThe lifecycle of a product and the lifecycle of the respective production equipment intersect in the production phase of the product, which at the same time represents the use phase of the production equipment. Product development and production development however follow more or less independent pathways, making use of different terminology ...
Vielhaber, Michael, Stoffels, Pascal
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mAbs, 2023 Excipients are added to biopharmaceutical formulations to enhance protein stability and enable the development of robust formulations with acceptable physicochemical properties, but the mechanism by which they confer stability is not fully understood ...
Chunting Zhang +11 more
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Disease progression modeling of the North Star Ambulatory Assessment for Duchenne Muscular Dystrophy
CPT: Pharmacometrics & Systems Pharmacology, 2023 Duchenne muscular dystrophy (DMD) is a rare genetic disorder caused by decreased or absent dystrophin gene leading to progressive muscle degeneration and weakness in young boys.
Jennifer E. Hibma +3 more
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mAbs, 2021 Monoclonal antibody (mAb) interchain disulfide bond reduction can cause a loss of function and negatively impact the therapeutic’s efficacy and safety.
Seo-Young Park +9 more
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A Tissue Engineering product development pathway [PDF]
, 2012 Tissue engineering is a field of inquiry and research that uses engineering techniques and principles of biological sciences to develop functional substitutes for reconstruction of damaged organs.
Falvo D'Urso Labate, Giuseppe Vittorio Ugo
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Effective Virtual Teams for New Product Development [PDF]
, 2012 At present, the existing literature shows that the factors which influence the effectiveness of virtual teams for new product development are still ambiguous.
Abdul Rashid, Salwa Hanim +3 more
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Requirements for Automotive LiDAR Systems
Sensors, 2022 Light detection and ranging (LiDAR) are fundamental sensors that help driving tasks for autonomous driving at various levels. Commercially available systems come in different specialized design schemes and involve plenty of specifications.
Zhuoqun Dai +5 more
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Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning
Bioengineering, 2022 Improving productivity to reduce the cost of biologics manufacturing and ensure that therapeutics can reach more patients remains a major challenge faced by the biopharmaceutical industry.
Qin He +15 more
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Deadlines in Product Development [PDF]
, 2012 Deadlines are common in product development and are often felt to be too harsh—many development efforts are still worth continuing at the time of mandated termination. We examine the value of deadlines from the agency-theoretic perspective. We consider a
Zhang, Juanjuan
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Alzheimer’s Research & Therapy, 2019 Background We previously investigated low doses (105 or 225 mg) of gantenerumab, a fully human monoclonal antibody that binds and removes aggregated amyloid-β by Fc receptor-mediated phagocytosis, in the SCarlet RoAD (SR) and Marguerite RoAD (MR) phase 3
Gregory Klein +13 more
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