Results 21 to 30 of about 26,594,875 (325)

Effective Virtual Teams for New Product Development [PDF]

open access: yes, 2012
At present, the existing literature shows that the factors which influence the effectiveness of virtual teams for new product development are still ambiguous.
Abdul Rashid, Salwa Hanim   +3 more
core   +7 more sources

Gantenerumab reduces amyloid-β plaques in patients with prodromal to moderate Alzheimer’s disease: a PET substudy interim analysis

open access: yesAlzheimer’s Research & Therapy, 2019
Background We previously investigated low doses (105 or 225 mg) of gantenerumab, a fully human monoclonal antibody that binds and removes aggregated amyloid-β by Fc receptor-mediated phagocytosis, in the SCarlet RoAD (SR) and Marguerite RoAD (MR) phase 3
Gregory Klein   +13 more
doaj   +1 more source

Deadlines in Product Development [PDF]

open access: yes, 2012
Deadlines are common in product development and are often felt to be too harsh—many development efforts are still worth continuing at the time of mandated termination. We examine the value of deadlines from the agency-theoretic perspective. We consider a
Zhang, Juanjuan
core   +1 more source

Optimization of Baseplate Hub Design for Swaging Operation

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
Swaging process is studied through a 2-D axisymmetric finite element model with non-linear material models and allowing large deformation. The effects of major baseplate hub geometrical parameters are studied for the case of a single actuator arm with ...
K.C. EE, Peter HAHN, Brett HOLAWAY
doaj   +1 more source

Two grass pollen tablets commercially available for allergy immunotherapy display different IgE epitope repertoires

open access: yesClinical and Translational Allergy, 2019
Background The distribution of Pooideae species varies across Europe. Especially, Timothy is less represented in Southern than in Northern Europe. Since allergenic cross-reactivity between pollens from different grasses is only partial, grass pollen ...
Thierry Batard   +7 more
doaj   +1 more source

Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics

open access: yesmAbs, 2020
Manufacturability of immunoglobulin G4 (IgG4) antibodies from the Chemistry, Manufacture, and Controls (CMC) perspective has received little attention during early drug discovery.
Zhiqiang Chen   +7 more
doaj   +1 more source

The Product Space Conditions the Development of Nations [PDF]

open access: yesScience, 2007
Economies grow by upgrading the products they produce and export. The technology, capital, institutions, and skills needed to make newer products are more easily adapted from some products than from others.
César A. Hidalgo   +3 more
semanticscholar   +1 more source

Microsystem Product Development

open access: yes, 2006
Over the last decade the successful design and fabrication of complex MEMS (MicroElectroMechanical Systems), optical circuits and ASICs have been demonstrated. Packaging and integration processes have lagged behind MEMS research but are rapidly maturing.
Polosky, M.-A., Garcia, E.-J.
openaire   +3 more sources

Tumor growth inhibition modeling to support the starting dose for dacomitinib

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2022
Dacomitinib is a second‐generation, irreversible EGFR tyrosine kinase inhibitor for first‐line treatment of patients with metastatic non‐small cell lung cancer and EGFR‐activating mutations.
Luke K. Fostvedt   +3 more
doaj   +1 more source

Baseline risk factors associated with immune related adverse events and atezolizumab

open access: yesFrontiers in Oncology, 2023
BackgroundImmune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer patients in the last decade, but immune-related adverse events (irAEs) pose significant clinical challenges.
Katrin Madjar   +6 more
doaj   +1 more source

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