Results 51 to 60 of about 26,594,875 (325)

Towards a New Framework for Product Development [PDF]

open access: yes, 2000
In the mid-1980s, Andreasen and Hein first described their model of Integrated Product Development. Many Danish companies quickly embraced the principles of integrated product development and adapted the model to their specific business and product ...
McAloone, TC, Robotham, AJ
core   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk   +9 more
wiley   +1 more source

Modelling the Product Development performance of Colombian Companies [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThis paper presents the general model of the Product Development Process (PDP) in the Metal mechanics Industry in Barranquilla-Colombia, since this sector contributes significantly to the productivity of this ...
Al-Ashaab, Ahmed   +4 more
core  

Type 1 interferon mediated signaling is indispensable for eliciting anti-tumor responses by Mycobacterium indicus pranii

open access: yesFrontiers in Immunology, 2023
IntroductionThe evolving tumor secretes various immunosuppressive factors that reprogram the tumor microenvironment (TME) to become immunologically cold.
Gargi Roy   +6 more
doaj   +1 more source

Hybrid organizations as a strategy for supporting new product development [PDF]

open access: yes, 2005
Alliances between large, well-established corporations and highly creative small companies or consultancies can be an effective method for promoting ...
Gander, Jonathan   +2 more
core   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig   +13 more
wiley   +1 more source

Experimental Investigation of a Large Tilting-Pad Journal Bearing—Comparison of a Flooded and Non-Flooded Design

open access: yesLubricants, 2022
In tilting-pad journal bearings (TPJB), power loss corresponds to the internal friction in the shearing of the oil. Besides the lubrication gap, intermediate spaces between the pads account for a notable amount of frictional losses.
Michael Stottrop   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Opportunities Assessment of Product Development Process in Industry 4.0

open access: yes, 2017
Nowadays, products customization by consumers tends to be one more variable in the manufacturing process, and smart factories will have to be able to customize what each customers have into consideration, adapting to the preferences.
K. Santos   +3 more
semanticscholar   +1 more source

From fundamental science to product : a bottom-up approach to sunscreen development [PDF]

open access: yes, 2018
Despite the pivotal role of ultraviolet (UV) radiation in sustaining life on Earth, overexposure to this type of radiation can have catastrophic effects, such as skin cancer. Sunscreens, the most common form of artificial protection against such harmful
Rodrigues, Natércia D. N.   +1 more
core   +1 more source

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