Results 61 to 70 of about 1,788,691 (267)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

RECOMBINANT MONOCLONAL ANTIBODIES FOR NEUROSCIENCE RESEARCH

IBRO Neuroscience Reports, 2023
Alexander Ball, Yung Lin Hsieh, Chun Kai Huang, Sega Huang, Ping Kuan Hsieh, Shang Ru Wu, Yue Yun Chang, Jiming Liu, Po Shin Peng, Chia Yun Chang, Chia Yi Lin   +10 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Bridging HDL Bits and Caffe: An Educational Path to AI Accelerator Design [PDF]

SHS Web of Conferences
An integrated educational pipeline is presented that bridges hardware description language (HDL) exercises with the Caffe deep learning framework, enabling progression from Verilog fundamentals to the deployment of convolutional neural network ...
Shanker Manjusha, Teo Tee Hui, Agarwal Harsh, Elsharkawy Mostafa Osama Abdellatif   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Big BIT maize experiment: A large multi‐location, multi‐year, multi‐tester, multi‐population predictive breeding validation study

The Plant Genome
The Big Breeding Innovation Team (Big BIT) maize (Zea mays L.) experiment was one of the largest genomic data‐informed predictive breeding validation studies ever conducted.
Michael Jines, Michael Chandler, Dean Podlich, Andrew Baumgarten, Deanne Wright, Amy Jacobson, Honghua Zhao, Jared Gogerty, Matthew Regennitter, Hsiao‐Yi Hung, Riley McDowell, Tom Tang, Christine Diepenbrock, Hoda Helmi, Carlos Messina, Andrew Ross, Gary Henke, Lindsay Spangler, Matthew Caldwell, Leah Stirling, Andres Reyes, Carla Gho, Mark Cooper, John Arbuckle, Matthew Smalley, Sandra Milach, Geoff Graham, Liviu Radu Totir   +27 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Benchmarking molecular conformer augmentation with context-enriched training: graph-based transformer versus GNN models

Journal of Cheminformatics
The field of molecular representation has witnessed a shift towards models trained on molecular structures represented by strings or graphs, with chemical information encoded in nodes and bonds.
Cecile Valsecchi, Jose A. Arjona-Medina, Natalia Dyubankova, Ramil Nugmanov   +3 more
doaj   +1 more source