Results 81 to 90 of about 6,360,422 (309)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Determination of Erucamide Slip Additive in Polypropylene Masterbatch: Comparison of Soxhlet and Dissolution-Precipitation Method [PDF]

Journal of Pure and Applied Chemistry Research
Erucamide is a long-chain carboxylic acid amide used as a slip agent in plastic films. In this research, the slip additive in polypropylene masterbatch with 6% erucamide content was extracted by comparing two methods which are dissolution-precipitation ...
Eka L. Purwaningtyas, Debby C. Wahyuni, Muhammad Y. Ramadhan, Silfi V. Susanti, Muhammad N. Ariesta, Chengli, Laily A. Agustina, Rakhma Febriani   +7 more
doaj  

On-column disulfide bond formation of monoclonal antibodies during Protein A chromatography eliminates low molecular weight species and rescues reduced antibodies

mAbs, 2020
Disulfide bond reduction, which commonly occurs during monoclonal antibody (mAb) manufacturing processes, can result in a drug substance with high levels of low molecular weight (LMW) species that may fail release specifications because the drug’s safety
Zhijun Tan, Vivekh Ehamparanathan, Tingwei Ren, Peifeng Tang, Laurel Hoffman, June Kuang, Peiran Liu, Chao Huang, Cheng Du, Li Tao, Letha Chemmalil, Angela Lewandowski, Sanchayita Ghose, Zheng Jian Li, Shijie Liu   +14 more
doaj   +1 more source

"Product Complexity and Economic Development" [PDF]

We rank 5,107 products and 124 countries according to the Hidalgo and Hausmann (2009) measures of complexity. We find that: (1) the most complex products are in machinery, chemicals, and metals, while the least complex products are raw materials and ...
Arnelyn Abdon, Jesus Felipe, Marife Bacate, Utsav Kumar   +3 more
core  

Towards Product Lining Model-Driven Development Code Generators [PDF]

, 2015
A code generator systematically transforms compact models to detailed code. Today, code generation is regarded as an integral part of model-driven development (MDD).
Roth, Alexander, Rumpe, Bernhard
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Product Development and International Trade [PDF]

We develop a multi-country, dynamic general equilibrium model of product innovation and international trade to study the creation of comparative advantage through research and development and the evolution of world trade over tune.
Elhanan Helpman, Gene M. Grossman
core  

Sustainable development strategies for product provision and manufacturing approaches [PDF]

, 2010
Manufacturing firms are under many pressures both financially and competitive which focus attention on the performance of their manufacturing processes.
Bateman, RJ, De Coster, R, Plant, AVC
core  

Characterizing the development of sectoral Gross Domestic Product composition

, 2013
We consider the sectoral composition of a country's GDP, i.e. the partitioning into agrarian, industrial, and service sectors. Exploring a simple system of differential equations we characterize the transfer of GDP shares between the sectors in the ...
Kropp, Jürgen P., Lutz, Raphael, Reusser, Dominik E., Rybski, Diego, Spies, Michael   +4 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source