Results 41 to 50 of about 760,836 (304)

Innovative approaches to nisin production [PDF]

open access: yesApplied Microbiology and Biotechnology, 2018
Nisin is a bacteriocin produced by Lactococcus lactis that has been approved by the Food Drug Administration for utilization as a GRAS status food additive. Nisin can inhibit spore germination and demonstrates antimicrobial activity against Listeria, Clostridium, Staphylococcus, and Bacillus species.
Özel, Burcu   +3 more
openaire   +9 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

THE IMPACT OF INNOVATION ON THE PERFORMANCE OF SMALL AND MEDIUM-SIZED ENTERPRISES IN RUSSIA: ЕMPIRICAL ANALYSIS

open access: yesСтратегические решения и риск-менеджмент
The article is devoted to the study of the impact of different types of innovation on the efficiency of Russian SMEs. The purpose of the study is to assess the importance of different types of innovation for Russian SMEs and to determine the impact of ...
P. D. Sererzhin
doaj   +1 more source

A Co-evolution Framework towards Stable Designs from Radical Innovations for Organizations Using IT

open access: yesJournal of Technology Management & Innovation, 2019
The purpose of this paper is to theoretically and empirically explore how organizations can enable radical product innovations to cumulate as stable designs.
Lakshminarayana Kompella
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Digitalization of educational organizations as a product- and process-innovation in the data economy: managerial and methodological aspects

open access: yesRussian Journal of Economics and Law
Objective: to reveal the essence of educational organizations’ digitalization as the implementation of product- and processinnovations in their innovation activity from the managerial viewpoint, including (here) innovation statistics in the data economy.
A. I. Shinkevich   +2 more
doaj   +1 more source

Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?

open access: yesTropical Medicine and Infectious Disease, 2020
African trypanosomiasis has been labelled as a ‘tool-deficient’ disease. This article reflects on the role that Product Development Partnerships (PDPs) have played in delivering new tools and innovations for the control and elimination of the
Emma Michelle Taylor, James Smith
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The effects of innovations on consumer satisfaction and loyalty [PDF]

open access: yesMarketing (Beograd. 1991)
In today’s market conditions, innovations are essential for maintaining competitive advantage and ensuring longterm business sustainability. It enables brands to differentiate themselves and respond to complex consumer needs.
Zlatanović Dejana   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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